In this work we report the linear and non-linear IR spectral response characterization of the CO bonds of $Penicillin$G sodium salt in $D_{2}O$ and in $DMSO-d6$ solutions. In order to better characterize the spectral IR features in the CO stretching region, broadband middle infrared pump-probe spectra are recorded. The role of hydrogen bonds in determining the inhomogeneous broadening and in tuning anharmonicity of the different types of oscillators is exploited. Narrow band pump experiments, at the three central frequencies of $\beta -lactam$, amide and carboxylate CO stretching modes, identify the couplings between the different types of CO oscillators opening the possibility to gather structural dynamic information. Our results show that the strongest coupling is between the $\beta -lactam$ and the carboxylate CO vibrational modes.

中文翻译：

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CO拉伸模式区中青霉素G的线性和非线性中红外光谱

在这项工作中，我们报告了线性和非线性红外光谱响应特征的CO键 $PËñ\mathrm{一世}C\mathrm{一世}升升\mathrm{一世}ñ$克钠盐$d_2Ø$ 和在 $d\mathrm{中号}\mathrm{小号}Ø-d6$解决方案。为了更好地表征CO拉伸区域中的光谱IR特征，记录了宽带中红外泵浦探针光谱。利用氢键在确定不同类型的振荡器的不均匀加宽和调节非谐性中的作用。窄带泵实验，在三个中心频率处$\beta -升\mathrm{一种}CŤ\mathrm{一种}米$，酰胺和羧酸盐的CO拉伸模式，确定了不同类型的CO振荡器之间的耦合，从而打开了收集结构动态信息的可能性。我们的结果表明，最强的耦合是$\beta -升\mathrm{一种}CŤ\mathrm{一种}米$ 以及羧酸盐一氧化碳的振动模式。