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Prostate cancer hijacks the microenvironment
Nature Cell Biology ( IF 17.3 ) Pub Date : 2021-01-08 , DOI: 10.1038/s41556-020-00616-3 Phillip Thienger , Mark A. Rubin
Nature Cell Biology ( IF 17.3 ) Pub Date : 2021-01-08 , DOI: 10.1038/s41556-020-00616-3 Phillip Thienger , Mark A. Rubin
Prostate cancer is difficult to treat because of molecular, cellular and clinical heterogeneity. Using single-cell RNA sequencing, a recent study reveals unexpected transcriptomic reprograming in immune cells and non-immune components of the tumour microenvironment, which may lead to viable therapeutic approaches against prostate cancer.
中文翻译:
前列腺癌劫持了微环境
由于分子,细胞和临床异质性,前列腺癌难以治疗。使用单细胞RNA测序,最近的一项研究揭示了肿瘤微环境的免疫细胞和非免疫成分中意外的转录组重编程,这可能导致针对前列腺癌的可行治疗方法。
更新日期:2021-01-08
中文翻译:
前列腺癌劫持了微环境
由于分子,细胞和临床异质性,前列腺癌难以治疗。使用单细胞RNA测序,最近的一项研究揭示了肿瘤微环境的免疫细胞和非免疫成分中意外的转录组重编程,这可能导致针对前列腺癌的可行治疗方法。