Flexible and printed biosensor devices can be used in wearable and disposable sensing systems for the daily management of health conditions. Organic thin-film transistors (OTFTs) are promising candidates for constructing such systems. Moreover, the integration of organic electronic materials and biosensors is of extreme interest owing to their mechanical and chemical features. To this end, the molecular recognition chemistry-based design for the interface between sensor devices and analyte solution is crucial to obtain accurate and reproducible sensing signals of targets, though little consideration has been given to this standpoint in the field of device engineering. Here, we report a printed OTFT on a 1 μm-thick film functionalized with a sensing material. Importantly, the fabricated device quantitatively responds to the addition of a protein immunological marker. These results provide guidelines for the development of effective healthcare tools.

柔性和印刷生物传感器设备可用于可穿戴和一次性传感系统中，以日常管理健康状况。有机薄膜晶体管（OTFT）是构建此类系统的有希望的候选者。此外，由于有机电子材料和生物传感器的机械和化学特性，它们的集成引起了极大的兴趣。为此，尽管在设备工程领域中很少有人考虑这一点，但基于分子识别化学的传感器设备与分析物溶液之间界面的设计对于获得目标的准确且可重现的传感信号至关重要。在这里，我们报告了在用传感材料功能化的1μm厚膜上的印刷OTFT。重要的，制造的设备对蛋白质免疫标记物的添加做出定量反应。这些结果为开发有效的医疗保健工具提供了指导。