Abstract

A simple, mild, eco-friendly, general, and convenient approach has been developed for the synthesis of structurally diverse 2-arylbenzothiazole derivatives from the reactions of 2-aminothiophenol and various aromatic aldehydes using camphor sulfonic acid a low cost, commercially available, efficient organo-catalyst in aqueous ethanol at room temperature. Under the same optimized conditions, a series of 2-arylbenzimidazoles was also synthesized starting from o-phenylenediamines and various aldehydes whereas synthesis of 3H-spiro[benzo[d]thiazole-2,3′-indolin]-2′-ones was accomplished from the reactions of 2-aminothiophenol and substituted isatins.

中文翻译：

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樟脑磺酸在室温下催化简单，容易且通用的合成2-芳基苯并噻唑，2-芳基苯并咪唑和3H-螺[苯并[d]噻唑-2,3'-吲哚] -2'-的方法。

摘要

已经开发了一种简单，温和，环保，通用且方便的方法，用于使用樟脑磺酸由2-氨基硫酚与各种芳族醛的反应合成结构多样的2-芳基苯并噻唑衍生物。有机催化剂在室温下于乙醇水溶液中。在相同的优化条件下，还从邻苯二胺和各种醛开始合成了一系列的2-芳基苯并咪唑，而合成了3 H-螺[苯并[ d ]噻唑-2,3'-吲哚] -2'-一个。由2-氨基苯硫酚与取代的靛红的反应完成。