Biochimica et Biophysica Acta (BBA) - Bioenergetics ( IF 3.4 ) Pub Date : 2021-01-08 , DOI: 10.1016/j.bbabio.2021.148368 Shane Austin 1 , Karin Nowikovsky 2
|
This review provides a retrospective on the role of osmotic regulation in the process of eukaryogenesis. Specifically, it focuses on the adjustments which must have been made by the original colonizing α-proteobacteria that led to the evolution of modern mitochondria. We focus on the cations that are fundamentally involved in volume determination and cellular metabolism and define the transporter landscape in relation to these ions in mitochondria as we know today. We provide analysis on how the cations interplay and together maintain osmotic balance that allows for effective ATP synthesis in the organelle.
中文翻译：
进化、阳离子转运和代谢中的线粒体渗透调节
这篇综述回顾了渗透调节在真核发生过程中的作用。具体来说，它侧重于导致现代线粒体进化的原始定植α-变形菌必须进行的调整。我们专注于从根本上参与体积测定和细胞代谢的阳离子，并定义与我们今天所知的线粒体中这些离子相关的转运蛋白景观。我们分析了阳离子如何相互作用并共同维持渗透平衡，从而在细胞器中有效地合成 ATP。
京公网安备 11010802027423号