Musca domestica is one of the major cosmopolitan pests in livestock facilities because it can be both a nuisance and a vector of pathogens to animals. Currently, treatment of animal manure with insect growth regulator (IGR) insecticides is among major practices to control M. domestica throughout the year over wide-ranging environmental temperatures. Fluctuation in daily or seasonal temperature is one of the most established factors impacting toxicity of insecticides against insect pests. In this study, the effect of posttreatment temperature (range, 20–36 °C) on the toxicity of eight IGRs: five chitin synthesis inhibitors (cyromazine, diflubenzuron, lufenuron, novaluron, triflumuron), two juvenile hormone analogs (methoprene, pyriproxyfen), and one ecdysone agonist (methoxyfenozide), was investigated against M. domestica. The toxicity of lufenuron and novaluron increased by 1.78 times over the range of 20–28 °C, and 2.25 and 1.83 times, respectively, over the range of 28–36 °C, with an overall increase by 4.00 and 3.26 times, respectively (i.e., positive temperature coefficient). In contrast, the toxicity of diflubenzuron, pyriproxyfen, and triflumuron decreased by 1.43, 1.89, and 2.10 times, respectively, over the range of 20–28 °C, and 1.70, 2.00, and 1.95 times, respectively, over the range of 28–36 °C, with an overall decrease by 2.43, 3.78, and 4.10 times, respectively. The toxicity of cyromazine, methoprene, and methoxyfenozide did not change significantly. Overall, these data will help stakeholders to choose appropriate insecticides for M. domestica control depending on the prevailing environmental temperature and to avoid misuse of insecticides that ultimately lead to environmental safety.

家蝇是家畜设施中主要的世界性害虫之一，因为它既可能是讨厌的动物，又是动物病原体的媒介。目前，用昆虫生长调节剂（IGR）杀虫剂处理动物粪便是控制家蝇的主要方法之一。一年四季都在广泛的环境温度下。每日或季节性温度的波动是影响杀虫剂对害虫毒性的最确定的因素之一。在这项研究中，后处理温度（范围20–36°C）对八种IGR毒性的影响：五种几丁质合成抑制剂（嘧啶，双氟苯隆，氟苯脲，诺富隆，三氟磺隆），两种少年激素类似物（美普,、吡pyr氧基） ，和一种蜕皮激素激动剂（甲氧基苯乙酰胺），针对家蝇。在20–28°C范围内，氟苯脲隆和壬基隆的毒性分别增加了1.78倍，在28–36°C范围内分别增加了2.25和1.83倍，总体上分别增加了4.00和3.26倍（即正温度系数）。相比之下，在20–28°C范围内，地氟苯隆，吡吡洛芬和三氟磺隆的毒性分别降低1.43、1.89和2.10倍，在28范围内分别降低1.70、2.00和1.95倍。 –36°C，分别降低了2.43、3.78和4.10倍。环丙嗪，甲基异戊二烯和甲氧基苯乙肼的毒性没有明显变化。总体而言，这些数据将有助于利益相关者为家蝇分枝杆菌选择合适的杀虫剂。 根据当时的环境温度进行控制，并避免滥用杀虫剂，最终导致环境安全。