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Dosimetric Comparison Between Carbon-ion Radiotherapy and Photon Radiotherapy for Stage I Esophageal Cancer
In Vivo ( IF 2.3 ) Pub Date : 2021-01-01 , DOI: 10.21873/invivo.12277
Yosuke Takakusagi 1 , Daisaku Yoshida 2 , Yohsuke Kusano 3 , Kio Kano 2 , Wataru Anno 2 , Keisuke Tsuchida 2 , Nobutaka Mizoguchi 2 , Itsuko Serizawa 2 , Hiroyuki Katoh 2 , Koh Imura 3 , Yoshiki Takayama 3 , Shinichi Minohara 3 , Tadashi Kamada 2
Affiliation  

Background/Aim: The present study aimed to compare the radiation dose distribution of carbon-ion radiotherapy (CIRT) for stage I esophageal cancer with three-dimensional conformal radiotherapy (3DCRT) and volumetric modulated arc therapy (VMAT). Patients and Methods: Fifteen patients with cT1bN0M0 esophageal cancer who received 3DCRT at Kanagawa Cancer Center between January 2014 and April 2019 were enrolled. The dose-volume histogram parameters of the target volume and normal organs planned with CIRT, 3DCRT, and VMAT were evaluated. Results: The homogeneity index for the target volume of CIRT was significantly lower than that of 3DCRT and VMAT. In addition, the radiation dose of CIRT to the heart, lungs, spinal cord, and skin was significantly lower than that of 3DCRT and VMAT. Conclusion: Favorable dose distributions with CIRT were demonstrated compared with 3DCRT and VMAT for esophageal cancer.

中文翻译:

碳离子放疗与光子放疗治疗Ⅰ期食管癌的剂量学比较

背景/目的:本研究旨在比较碳离子放疗 (CIRT) 与三维适形放疗 (3DCRT) 和容积调制弧疗法 (VMAT) 治疗 I 期食管癌的辐射剂量分布。患者和方法:招募了 2014 年 1 月至 2019 年 4 月在神奈川癌症中心接受 3DCRT 的 15 名 cT1bN0M0 食管癌患者。评估了 CIRT、3DCRT 和 VMAT 计划的靶体积和正常器官的剂量体积直方图参数。结果:CIRT靶体积的均匀性指数明显低于3DCRT和VMAT。此外,CIRT对心脏、肺、脊髓和皮肤的辐射剂量显着低于3DCRT和VMAT。结论:
更新日期:2021-01-01
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