Detecting carrier couples through premarital screening implementation is an effective way of controlling thalassaemia. The aim of this study was to investigate the knowledge of university students towards premarital screening and their possible involvement in an at-risk marriage. Students (n = 976) were chosen randomly from Jordanian universities. The questionnaire consisted of three sections: socio-demographical data, the students’ knowledge about the screening programme, and finally their beliefs and future decisions related to it. Most (90%) participants were aware of the premarital screening availability. Females had significantly better understanding of premarital screening compared to males. Despite the majority of the participants not wanting to go ahead with at-risk marriages, 23% would not be deterred from marrying their anticipated partner and believed engaging in at-risk marriage was a valid idea. We suggest providing more effective educational programmes, genetic counselling and free prenatal diagnosis for at-risk couples.

通过实施婚前筛查检测携带者夫妇是控制地中海贫血的有效途径。本研究的目的是调查大学生对婚前筛查的了解以及他们可能参与的风险婚姻。学生（n= 976) 是从约旦大学中随机选择的。问卷由三部分组成：社会人口数据、学生对筛查计划的了解，最后是他们的信念和与之相关的未来决定。大多数（90%）参与者都知道婚前筛查的可用性。与男性相比，女性对婚前筛查的理解明显更好。尽管大多数参与者不想继续有风险的婚姻，但 23% 的人不会阻止与他们预期的伴侣结婚，并认为从事有风险的婚姻是一个有效的想法。我们建议为高危夫妇提供更有效的教育计划、遗传咨询和免费产前诊断。