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Psycho-demographic profile in severe asthma and effect of emotional mood disorders and hyperventilation syndrome on quality of life
BMC Psychology ( IF 2.7 ) Pub Date : 2021-01-06 , DOI: 10.1186/s40359-020-00498-y
Lucía Dafauce , David Romero , Carlos Carpio , Paula Barga , Santiago Quirce , Carlos Villasante , María Fe Bravo , Rodolfo Álvarez-Sala

Severe asthma affects a small population but carries a high psychopathological risk. Therefore, the psychodemographic profile of these patients is of interest. A substantial prevalence of anxiety, depression, alexithymia and hyperventilation syndrome in severe asthma is known, but contradictory results have been observed. These factors can also affect patients’ quality of life. For this reasons, our purpose is to evaluate the psychodemographic profile of patients with severe asthma and assess the prevalence of anxiety, depression, alexithymia and hyperventilation syndrome and their impact on the quality of life of patients with severe asthma. A cross-sectional study of 63 patients with severe asthma. Their psychodemographic profile was evaluated using the Hospital Anxiety and Depression Scale (HADS), Toronto Alexithymia Scale (TAS-20), Nijmegen questionnaire and Asthma Control Test (ACT) to determine the state of anxiety and depression, alexithymia, hyperventilation syndrome and control of asthma, respectively. Quality of life was assessed with the Mini Asthma Quality of Life Questionnaire (Mini-AQLQ). The mean age was 60 ± 13.6 years. Personal psychopathological histories were found in 65.1% of participants, and 8% reported previous suicidal attempts. The rate of anxiety and/or depression (HADS ≥ 11) was 68.3%. These patients present higher scores on the TAS-20 (p < 0.001) for the level of dyspnea (p = 0.021), and for emotional function (p = 0.017) on the Mini-AQLQ, compared with patients without anxiety or depression. Alexithymia (TAS-20 ≥ 61) was observed in 42.9% of patients; these patients were older (p = 0.037) and had a higher HADS score (p = 0.019) than patients with asthma without alexithymia. On the other hand, patients with hyperventilation syndrome (Nijmegen ≥ 23) scored higher on the HADS (p < 0.05), on the Mini-AQLQ (p = 0.002) and on the TAS-20 (p = 0.044) than the group without hyperventilation syndrome. Quality of life was related to anxiety-depression symptomatology (r = − 0.302; p = 0.016) and alexithymia (r = − 0.264; p = 0.036). Finally, the Mini-AQLQ total score was associated with the Nijmegen questionnaire total score (r = − 0.317; p = 0.011), and the activity limitation domain of the Mini-AQLQ correlated with the ACT total score (r = 0.288; p = 0.022). The rate of anxiety, depression, alexithymia and hyperventilation syndrome is high in patients with severe asthma. Each of these factors is associated with a poor quality of life.

中文翻译:

严重哮喘的人口统计学特征以及情绪情绪障碍和换气过度综合征对生活质量的影响

严重的哮喘只影响少数人群,但精神病风险较高。因此,这些患者的心电图谱是令人感兴趣的。已知严重哮喘中焦虑,抑郁,智力低下和换气过度综合征的患病率很高,但观察到矛盾的结果。这些因素也会影响患者的生活质量。因此,我们的目的是评估重度哮喘患者的心电图谱特征,并评估焦虑,抑郁,运动障碍和过度换气综合征的患病率及其对重度哮喘患者生活质量的影响。对63例严重哮喘患者的横断面研究。他们使用医院焦虑和抑郁量表(HADS),多伦多Alexithymia量表(TAS-20)对他们的心电图进行了评估,奈梅亨问卷和哮喘控制测试(ACT)分别用于确定焦虑和抑郁的状态,运动障碍,过度换气综合征和哮喘的控制。生活质量通过《迷你哮喘生活质量问卷》(Mini-AQLQ)进行评估。平均年龄为60±13.6岁。在65.1%的参与者中发现了个人的心理病理学历史,并且8%的人报告了先前的自杀企图。焦虑和/或抑郁(HADS≥11)的发生率为68.3%。与没有焦虑或抑郁的患者相比,这些患者在Mini-AQLQ上的呼吸困难水平(p = 0.021)和情绪功能(p = 0.017)在TAS-20上得分更高(p <0.001)。在42.9%的患者中发现了Alexithymymia(TAS-20≥61);这些患者年龄较大(p = 0.037),HADS评分较高(p = 0。019)比没有无精神障碍的哮喘患者。另一方面,过度换气综合征(Nijmegen≥23)的患者在HADS(p <0.05),Mini-AQLQ(p = 0.002)和TAS-20(p = 0.044)上的得分均高于未使用该组的患者。换气过度综合征。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。另一方面,过度换气综合征(Nijmegen≥23)的患者在HADS(p <0.05),Mini-AQLQ(p = 0.002)和TAS-20(p = 0.044)上的得分均高于未使用该组的患者。换气过度综合征。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。另一方面,过度换气综合征(Nijmegen≥23)的患者在HADS(p <0.05),Mini-AQLQ(p = 0.002)和TAS-20(p = 0.044)上的得分均高于未使用该组的患者。换气过度综合征。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。换气过度综合征(Nijmegen≥23)的患者在HADS,Mini-AQLQ(p = 0.002)和TAS-20(p = 0.044)上的得分均高于没有换气过度综合征的组。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。换气过度综合征(Nijmegen≥23)的患者在HADS,Mini-AQLQ(p = 0.002)和TAS-20(p = 0.044)上的得分均高于没有换气过度综合征的组。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。044)比无过度换气综合征的组高。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。044)比无过度换气综合征的组高。生活质量与焦虑抑郁症状(r = − 0.302; p = 0.016)和运动障碍(r = − 0.264; p = 0.036)有关。最后,Mini-AQLQ总分与奈梅亨问卷调查总分相关(r = − 0.317; p = 0.011),Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。011),而Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。011),而Mini-AQLQ的活动限制域与ACT总分相关(r = 0.288; p = 0.022)。严重哮喘患者的焦虑,抑郁,智力低下和过度换气综合征的发生率很高。这些因素中的每一个都与生活质量差有关。
更新日期:2021-01-07
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