Objective. To develop consensus recommendations for the use of repetitive transcranial magnetic stimulation (rTMS) as an adjunct intervention for upper extremity motor recovery in stroke rehabilitation clinical trials. Participants. The Canadian Platform for Trials in Non-Invasive Brain Stimulation (CanStim) convened a multidisciplinary team of clinicians and researchers from institutions across Canada to form the CanStim Consensus Expert Working Group. Consensus Process. Four consensus themes were identified: (1) patient population, (2) rehabilitation interventions, (3) outcome measures, and (4) stimulation parameters. Theme leaders conducted comprehensive evidence reviews for each theme, and during a 2-day Consensus Meeting, the Expert Working Group used a weighted dot-voting consensus procedure to achieve consensus on recommendations for the use of rTMS as an adjunct intervention in motor stroke recovery rehabilitation clinical trials. Results. Based on best available evidence, consensus was achieved for recommendations identifying the target poststroke population, rehabilitation intervention, objective and subjective outcomes, and specific rTMS parameters for rehabilitation trials evaluating the efficacy of rTMS as an adjunct therapy for upper extremity motor stroke recovery. Conclusions. The establishment of the CanStim platform and development of these consensus recommendations is a first step toward the translation of noninvasive brain stimulation technologies from the laboratory to clinic to enhance stroke recovery.

中文翻译：

---

加拿大无创脑刺激试验平台 (CanStim) 上肢运动中风康复试验中重复经颅磁刺激的共识建议

客观的。制定关于使用重复经颅磁刺激 (rTMS) 作为中风康复临床试验中上肢运动恢复辅助干预的共识建议。参与者。加拿大非侵入性脑刺激试验平台 (CanStim) 召集了一个由来自加拿大各地机构的临床医生和研究人员组成的多学科团队，组成了 CanStim 共识专家工作组。共识过程。确定了四个共识主题：（1）患者群体，（2）康复干预，（3）结果测量，以及（4）刺激参数。主题负责人对每个主题进行了全面的证据审查，在为期 2 天的共识会议期间，专家工作组使用加权点投票共识程序就使用 rTMS 作为运动中风恢复康复临床试验的辅助干预的建议达成共识。结果。根据现有的最佳证据，就确定目标卒中后人群、康复干预、客观和主观结果以及用于评估 rTMS 作为上肢运动性卒中恢复辅助治疗效果的康复试验的特定 rTMS 参数的建议达成了共识。结论。CanStim 平台的建立和这些共识建议的制定是将无创脑刺激技术从实验室转化为临床以促进中风康复的第一步。