A blended FC-V-50 and TZ-001 polymer-based microdisk laser was fabricated by the ink-jet printing method and used for biosensing applications. The FC-V-50 polymer has a negative charge due to the presence of carboxyl functional groups, and the TZ-001 polymer has a positive charge due to the tertiary amine group at a pH of seven. In biosensing applications, non-specific adsorption due to opposite charges of biomolecules and microdisk surfaces can adversely affect the performance of the biosensor. By mixing FC-V-50 and TZ-001 polymers in different ratios, the microdisk surface charge was controlled, and the non-specific adsorption of bovine serum albumin and lysozyme was studied. In addition, the label-free biosensing of streptavidin was demonstrated using a blended polymer-based microdisk laser. This work reports, to the best of our knowledge, the first demonstration of a blended polymer microdisk laser for controlling the non-specific adsorption of biomolecules.

中文翻译：

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用于控制生物分子非特异性吸附的喷墨打印、混合聚合物基微盘谐振器

通过喷墨打印方法制造了一种混合的 FC-V-50 和 TZ-001 聚合物基微盘激光器，并用于生物传感应用。FC-V-50 聚合物由于存在羧基官能团而带负电荷，TZ-001 聚合物由于叔胺基团在 pH 值为 7 时带正电荷。在生物传感应用中，由于生物分子和微盘表面的相反电荷导致的非特异性吸附会对生物传感器的性能产生不利影响。通过以不同比例混合FC-V-50和TZ-001聚合物，控制微盘表面电荷，研究了牛血清白蛋白和溶菌酶的非特异性吸附。此外，链霉亲和素的无标记生物传感使用基于聚合物的混合微盘激光器进行了证明。据我们所知，这项工作报告，