Discussions about the responsible advancement of synthetic biology science are at fever pitch. Commentators from across the globe are calling for greater integrated science investments and more inclusive governance processes in the development and implementation of these potentially disruptive technologies. We take stock of the promises and realities of science integration by sharing our experiences of embarking on this very challenge in Australia. We conclude by offering suggestions for bringing about the enabling conditions for improved integration across the natural and social sciences. Four key actions are articulated to help pivot synthetic biology toward a more integrated scientific endeavor: (a) formalizing inclusivity from inception to project conclusion; (b) valuing differing philosophical positions as a strength rather than a barrier; (c) accepting that integration takes persistence and communication but is immensely rewarding; and (d) promoting meaningful interactions, such as pursuing joint opportunities, co-designing and co-publishing research. We argue that these actions are key enablers for realizing science integration in synthetic biology.

中文翻译：

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合成生物学整合的承诺和现实：社会科学的观点

关于合成生物学科学的负责任进步的讨论正处于高潮。来自全球的评论员呼吁在这些潜在破坏性技术的开发和实施中进行更大的综合科学投资和更具包容性的治理流程。我们通过分享我们在澳大利亚迎接这一挑战的经验来评估科学整合的前景和现实。最后，我们提出建议，为改善自然科学和社会科学的整合创造有利条件。阐明了四项关键行动，以帮助将合成生物学转向更加综合的科学努力：(a) 从开始到项目结束的形式化包容性；(b) 将不同的哲学立场视为一种力量而不是障碍；(c) 接受整合需要坚持和沟通，但会带来巨大的回报；(d) 促进有意义的互动，例如寻求联合机会、共同设计和共同发表研究。我们认为，这些行动是在合成生物学中实现科学整合的关键推动因素。