The present study examined the in vitro and in vivo bone formation and adhesion ability on the surface of a titanium dental implant made by plasma electrolytic oxidation (PEO) in electrolytes containing bioactive ions. To achieve this goal, screw-shaped fabricated Ti-6Al-4V alloy implants were processed via PEO using an electrolyte solution containing calcium (Ca), phosphorous (P), magnesium (Mg), zinc (Zn), strontium (Sr), silicon (Si), and manganese (Mn) species. The screw implants doped with bioactive elements via PEO were placed in rabbit tibia, and the results were compared to the sand-blasted Ti-6Al-4V alloy implants. At eight-week post-surgery, there was no significant difference in the values of removal torque between sand-blasted and PEO-treated implants. However, it was observed that the PEO treatment of dental implants led to the formation of more periphery bone as compared to the case of sand-blasted implants. Accordingly, the PEO-treated implants have the potential to be used as promising materials for dental applications.

中文翻译：

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在含骨离子的溶液中通过等离子体电解氧化促进种植体表面的骨形成和粘附能力

本研究检查了在含有生物活性离子的电解质中，通过等离子体电解氧化（PEO）制成的钛牙科植入物在体外和体内的骨形成和粘附能力。为了达到这个目标，使用含有钙（Ca），磷（P），镁（Mg），锌（Zn），锶（Sr），硅（Si）和锰（Mn）物种。将通过PEO掺杂了生物活性元素的螺钉植入物放置在兔胫骨中，并将结果与​​喷砂的Ti-6Al-4V合金植入物进行了比较。术后八周，喷砂和PEO处理的植入物的去除扭矩值无明显差异。然而，观察到，与喷砂植入物相比，PEO处理牙植入物导致形成更多的周围骨骼。因此，经PEO处理的植入物具有用作牙科应用的有前途的材料的潜力。