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Analysis of arglabin and its derivatives using high-performance liquid chromatography
Phytochemical Analysis ( IF 3.0 ) Pub Date : 2021-01-06 , DOI: 10.1002/pca.3023
Sergazy M Adekenov 1 , Saltanat T Shamilova 1 , Ilya A Khabarov 1
Affiliation  

The chemical modification of arglabin, a natural sesquiterpene lactone, has garnered significant attention because it comprises a guaianolide structure that exhibits antitumour and immunomodulating properties. Its primarily derived from Artemisia glabella Kar. et Kir. Physicochemical characterisation of commercial anititumour drugs based on arglabin can be time-consuming and expensive; thus, high-performance liquid chromatography (HPLC) is an optimal method to identify arglabin and its derivatives.

中文翻译:

使用高效液相色谱法分析 arglabin 及其衍生物

arglabin 是一种天然倍半萜内酯,其化学修饰引起了极大的关注,因为它包含具有抗肿瘤和免疫调节特性的愈创木酚内酯结构。它主要来自青蒿。和基尔。基于 arglabin 的商业抗肿瘤药物的物理化学表征可能既耗时又昂贵;因此,高效液相色谱 (HPLC) 是鉴定 arglabin 及其衍生物的最佳方法。
更新日期:2021-01-06
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