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Clinical characteristic and epidemiological features of SARS CoV‐2 disease patients from a COVID‐19 designated hospital in New Delhi
Journal of Medical Virology ( IF 6.8 ) Pub Date : 2021-01-06 , DOI: 10.1002/jmv.26777
Sonal Saxena 1 , Vikas Manchanda 1 , Tanu Sagar 1 , Nazia Nagi 1 , Oves Siddiqui 1 , Abhishek Yadav 1 , Nitin Arora 1 , Faria Hasan 1 , Kavita Meena 1 , Pradeep Bharti 1 , Neha Rana 1 , Sikander Hayat 1 , Sanchita Tuteja 1 , Ajeet Yadav 1 , Devyani Puri 1 , Palak Pumma 1 , Khyati 1 , Ananya Arora 1 , Jainandra 1 , Sunidhi Shreya 1 , Suresh Kumar 2 , Nandini Sharma 1
Affiliation  

Severe acute respiratory syndrome coronavirus 2 (SARS CoV‐2) infection is rapidly evolving as a serious global pandemic. The present study describes the clinical characteristics of SARS CoV‐2 infection patients. The samples were subjected to reverse‐transcription polymerase chain reaction or Rapid Antigen test for diagnosis of SARS CoV‐2. A cohort of 3745 patients with confirmed diagnosis of SARS CoV‐2 infection in a tertiary care center in New Delhi, India were included in this study. Data were collected from offline and online medical records over a period of 6 months. Amongst 3745 SARS CoV‐2 infected patients, 2245 (60%) were symptomatic and 1500 (40%) were asymptomatic. Most common presenting symptom was cough (49.3%) followed febrile episodes (47.1%), breathlessness (42.7%), and sore throat (35.1%). Cough along with breathlessness (24.1) was the most common combination of symptoms followed by fever with cough (22.7). The most common comorbidity found among symptomatic group was diabetes (42.5%) followed by hypertension (21.4%) and chronic kidney disease (18%). Comorbidities like diabetes mellitus, chronic diseases of lungs, heart, and kidneys were found to be common in symptomatic group and this was found to be statistically significant (p < .05). COVID‐19 is an evolving disease and data from our study help in understanding the clinic‐epidemiological profile of patients.

中文翻译:


新德里一家 COVID-19 定点医院 SARS CoV-2 疾病患者的临床特征和流行病学特征



严重急性呼吸综合征冠状病毒 2 (SARS CoV-2) 感染正在迅速演变为严重的全球流行病。本研究描述了 SARS CoV-2 感染患者的临床特征。对样本进行逆转录聚合酶链反应或快速抗原检测以诊断 SARS CoV-2。这项研究纳入了印度新德里一家三级护理中心的 3745 名确诊为 SARS CoV-2 感染的患者。数据是从 6 个月内的线下和在线医疗记录中收集的。在 3745 名 SARS CoV-2 感染患者中,2245 名(60%)有症状,1500 名(40%)无症状。最常见的症状是咳嗽(49.3%),其次是发热(47.1%)、呼吸困难(42.7%)和喉咙痛(35.1%)。咳嗽和呼吸困难(24.1)是最常见的症状组合,其次是发烧和咳嗽(22.7)。有症状人群中最常见的合并症是糖尿病(42.5%),其次是高血压(21.4%)和慢性肾病(18%)。糖尿病、肺、心、肾等慢性疾病等合并症在有症状组中很常见,并且具有统计学意义 ( p < .05)。 COVID-19 是一种不断发展的疾病,我们的研究数据有助于了解患者的临床流行病学概况。
更新日期:2021-02-17
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