This study was conducted to evaluate the adverse effects of atrazine on hematology, biochemistry and genotoxicity of snow trout (Schizothorax plagiostomus). Almost all treated groups presented considerably (P < 0.05) lesser values of hematocrit, hemoglobin, WBC, RBC, MCH, MCHC, monocytes and lymphocytes while significantly higher values of HCT and platelets are observed. A Significant decrease is observed in sodium, calcium, potassium, phosphorous, triglycerides, creatinine, urea, and total protein contents whereas, a significant increase is observed in cholesterol and glucose level. Significant (P < 0.05) alterations are observed in enzyme activities of all treated groups. DNA damage was observed at the concentrations (2–4 ppm). Results showed that Comet assay is reliable for evaluating the toxicity and is helpful in environmental monitoring programs.

进行这项研究以评估阿特拉津对雪鳟（Schizothorax plagiostomus）的血液学，生化和遗传毒性的不利影响。几乎所有治疗组 的血细胞比容，血红蛋白，WBC，RBC，MCH，MCHC，单核细胞和淋巴细胞的值均显着降低（P <0.05），而观察到的HCT和血小板值则明显更高。钠，钙，钾，磷，甘油三酸酯，肌酐，尿素和总蛋白含量均显着下降，而胆固醇和葡萄糖水平则显着上升。显著（P ＜0.05）观察到所有处理组的酶活性都有变化。在浓度（2-4 ppm）下观察到DNA损伤。结果表明，彗星试验可用于评估毒性，并且对环境监测程序很有帮助。