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Intra and extracellular effects of benzo [α] pyrene on liver, gill and blood of Caspian White fish (Rutilus frissi kutum): Cyto-genotoxicity and histopathology approach
Marine Pollution Bulletin ( IF 5.3 ) Pub Date : 2021-01-07 , DOI: 10.1016/j.marpolbul.2020.111942
Milad Esmaeilbeigi , Mohammad Reza Kalbassi , Javad Seyedi , Mohammad Behzadi Tayemeh , Jamshid Amiri Moghaddam

Southern parts of the Caspian Sea have been faced with a diverse range of oil pollutants. Therefore, this study was designed to evaluate the effects of relevant environmental concentrations of benzo[α]pyrene (BαP) on liver, gill, and blood of Caspian White fish. To this end, 150 fingerling fish (6.5 ± 0.8 g) were exposed to under, near and over environmental concentrations of BαP (i.e. 50, 100, and 200 ppb, respectively) and two control groups for 21 days. Following exposure to BαP, generally, DNA damage increased in the liver and gill cells as well as the frequency of micro- and bi-nucleated erythrocytes in a time and concentration-dependent pattern. In addition, the liver and gill tissues displayed several histopathological lesions. Together, the findings are warning the health status of the Caspian Sea due to an ever-increasing concentration of BαP through using Caspian White fish as an ecological model.



中文翻译:

苯并[α] on对里海白鱼(Rutilus frissi kutum)肝,g和血液的细胞内和细胞外作用:细胞遗传毒性和组织病理学方法

里海南部地区面临着各种各样的石油污染物。因此,本研究旨在评估相关环境浓度的苯并[α] py(BαP)对里海白鱼的肝脏,腮和血液的影响。为此,将150只鱼种鱼(6.5±0.8 g)暴露于低于,接近和高于环境浓度的BαP(分别为50、100和200 ppb)和两个对照组,持续21天。通常,在暴露于BαP后,肝脏和g细胞的DNA损伤以及微核和双核红细胞的频率以时间和浓度依赖性的方式增加。另外,肝和腮组织显示出若干组织病理学损害。一起,

更新日期:2021-01-07
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