Carpal tunnel syndrome (CTS) is a disorder that affects the median nerve at the wrist sufficient to cause impairment of nerve function. Elevated carpal tunnel pressure (CTP) leads to median nerve pathology, sensory, and motor changes in CTS patient. The techniques to quantify CTP used in clinic are invasive. This study aimed to investigate the feasibility of a noninvasive ultrasound vibro–elastography (UVE) to predict CTP in CTS patients and healthy individuals. The magnitudes of shear wave speed ratio (rSWS) of the 10 CTS patients (10 hands) and 6 healthy individuals (12 hands), and 10 cadaveric hands were compared using UVE. The ratios of intra to extra-carpal tunnel SWS in CTS patients was significantly higher than those in the healthy individuals (p = 0.0008) and cadaveric hands (p = 0.0015) with 500-g tendon tension. We estimated the CTP in the carpal tunnel using the mean rSWS of each group obtained from the present study and the linear approximation obtain from cadaveric hands data with 500-g tendon tension (y = 0.0036x + 1.1413). These results indicated that the elevated pressure applied to the 3rd flexor digitorum superficialis tendon in the carpal tunnel of CTS patients resulted in faster shear wave propagation. These results show that UVE was useful to indirectly estimate the CTP by measuring the rSWS; thus, they are potentially useful for the early diagnosis and assessment of CTS.

腕管综合症（CTS）是一种影响腕部正中神经的疾病，足以引起神经功能损害。腕管压力（CTP）升高会导致CTS患者中位神经病理，感觉和运动改变。量化临床中使用的CTP的技术是侵入性的。本研究旨在探讨无创超声弹性弹力描记术（UVE）预测CTS患者和健康个体CTP的可行性。使用UVE比较了10例CTS患者（10手）和6个健康个体（12手）和10具尸体手的剪切波速度比（rSWS）的大小。CTS患者腕内和腕外隧道SWS的比率显着高于具有500 g肌腱张力的健康个体（p = 0.0008）和尸体手（p = 0.0015）。我们使用从本研究中获得的每组均值rSWS以及从尸体手部数据获得的500 g肌腱张力的线性近似值（y = 0.0036x + 1.1413）来估计腕管的CTP。这些结果表明，在CTS患者腕管中施加到第三腕浅指肌腱的压力升高导致剪切波传播更快。这些结果表明，UVE可用于通过测量rSWS间接估算CTP。因此，它们可能对CTS的早期诊断和评估有用。这些结果表明，在CTS患者腕管中施加到第三腕浅指肌腱的压力升高导致剪切波传播更快。这些结果表明，UVE可用于通过测量rSWS间接估算CTP。因此，它们可能对CTS的早期诊断和评估有用。这些结果表明，在CTS患者腕管中施加到第三腕浅指肌腱的压力升高导致剪切波传播更快。这些结果表明，UVE可用于通过测量rSWS间接估算CTP。因此，它们可能对CTS的早期诊断和评估有用。