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Binding and crossing: Methods for the characterization of membrane-active peptides interactions with membranes at the molecular level
Archives of Biochemistry and Biophysics ( IF 3.8 ) Pub Date : 2021-01-07 , DOI: 10.1016/j.abb.2021.108751
Sachon Emmanuelle , Walrant Astrid , Sagan Sandrine , Cribier Sophie , Rodriguez Nicolas

Antimicrobial and cell-penetrating peptides have been the object of extensive studies for more than 60 years. Initially these two families were studied separately, and more recently parallels have been drawn. These studies have given rise to numerous methodological developments both in terms of observation techniques and membrane models. This review presents some of the most recent original and innovative developments in this field, namely droplet interface bilayers (DIBs), new fluorescence approaches, force measurements, and photolabelling.



中文翻译:

结合和杂交:在分子水平上表征膜活性肽与膜相互作用的方法

六十多年来,抗菌肽和细胞穿透肽一直是广泛研究的目标。最初,这两个家族是分别研究的,最近又有相似之处。这些研究在观察技术和膜模型方面引起了许多方法学的发展。这篇综述介绍了该领域的一些最新的原创性和创新性发展,即液滴界面双层(DIB),新的荧光方法,力测量和光标记。

更新日期:2021-01-19
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