Human rabies is a significant public health concern in Tunisia. However, the spatiotemporal spread pattern of rabies in dogs, the major reservoir and vector, and its determinants are poorly understood. We collected geographic locations and timeline of reported animal rabies cases in the region of CapBon (study area), for the years 2015–2019 and integrated them in Geographical Information System (GIS) approach to explore the spatio-temporal pattern of dog rabies. The results show that roads and irrigated areas can act as ecological corridors to viral spread. Our study showed that there was a significant seasonal variation in the number of cases of rabies recorded, with a strong peak in spring and lower peak in winter and summer. These findings may play a role in updating and directing public health policy, as well as providing opportunities for authorities to explore control options in time and space. A better knowledge of the ecology and dog population dynamics is still necessary and important to achieve an effective rabies control.

狂犬病是突尼斯的重要公共卫生问题。但是，人们对狂犬病在犬，主要水库和媒介中的时空传播模式及其决定因素了解得很少。我们收集了CapBon（研究区域）2015-2019年间报告的动物狂犬病病例的地理位置和时间表，并将其整合到地理信息系统（GIS）方法中，以探索狗狂犬病的时空格局。结果表明，道路和灌溉区可作为病毒传播的生态走廊。我们的研究表明，记录的狂犬病病例数存在明显的季节性变化，春季高峰高峰，冬季和夏季高峰较低。这些发现可能在更新和指导公共卫生政策方面发挥作用，并为当局提供了探索时空控制方案的机会。更好地了解生态和狗的种群动态对于实现有效的狂犬病控制仍然是必要且重要的。