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Design and Analysis of Gate Overlapped/Underlapped NWFET Based Lable Free Biosensor
Silicon ( IF 3.4 ) Pub Date : 2021-01-06 , DOI: 10.1007/s12633-020-00880-w
Shamshad Alam , Ashish Raman , Balwinder Raj , Naveen Kumar , Sarabdeep Singh

In this paper, gate all around (GAA) nanowire P-channel FET label free biosensor is proposed with cavity. Proposed structure is label free so it doesn’t require selective material for specific biomolecule enzymes. High surface to volume ratio provide good sensitivity which is crucial for any biosensor application. To sense the kind of biomolecule, there is a cavity created at the gate, so biological elements like enzymes interact with cavity and it changes the carrier concentration which in turn changes the current. In addition to this, first biosensor structure is analyzed with cavity at the source side and second structure is analyzed with cavity at the drain side. Length of cavity is varied from 10 nm to 40 nm for optimization of the proposed biosensor structure. This biosensor is used to find the amount of biomolecule present in aqueous solution through their enzymes. To estimate the sensing capability of this sensor, testing is done using glucose molecules. We observed comparatively better sensitivity when cavity is placed at drain side.



中文翻译:

基于门极重叠/非重叠NWFET的无标签生物传感器的设计与分析

在本文中,提出了带有腔的全栅(GAA)纳米线P沟道FET无标签生物传感器。拟议的结构没有标签,因此不需要用于特定生物分子酶的选择性材料。高的表面体积比提供了良好的灵敏度,这对于任何生物传感器应用都是至关重要的。为了检测生物分子的种类,在闸门处创建了一个空腔,因此诸如酶之类的生物元素与空腔相互作用,并改变了载流子浓度,进而改变了电流。除此之外,第一生物传感器结构在源极侧具有空腔,第二结构在漏极侧具有空腔。腔的长度从10 nm到40 nm不等,以优化所提出的生物传感器结构。该生物传感器用于通过其酶找出水溶液中存在的生物分子的量。为了估计该传感器的感测能力,使用葡萄糖分子进行了测试。当将腔放置在漏极侧时,我们观察到相对较好的灵敏度。

更新日期:2021-01-07
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