Background: Assessing the quality of life in HIV/AIDS patients is of great importance not only for evaluating the effect of the disease, but also to measure the impact of the interventions in order to improve their quality of life in clinical researches. Therefore, this study aimed to systematically review the quality of life of HIV/AIDS patients in Iran. Methods: In this systematic review and meta-analysis, the literature search using the related chain of keywords was conducted from 1 Jan 1987 to 30 Apr 2019 in PubMed, Scopus, Web of Science, Embase, Iranian Scientific Information Database (SID), and Magiran. Moreover, hand search of the key journals and the gray literature was performed. The meta-analysis was performed by CMA2 software. Results: Out of the 1576 retrieved records, eight studies met the inclusion criteria. The average age of the patients was 37.15 ± 9.46 years. The average score of quality of life before and after sensitivity analysis was (39.13 [28.36–49.901 95% CI P>0.000] vs. 49.05 [46.31–51.79 95% CI P>0.000]). Moreover, the average score of quality of life was respectively 38.86±3.83 vs. 40±6.37 among married compared with single patients, 56.33±4.67 vs. 43.64±1.94 for employment vs. unemployment status. While quality of life was measured in terms of education level, the score was 29.59±9.34 vs. 41.65±4.45 in the individuals with primary school versus academic education. Conclusion: The QOL score of the HIV/AIDS patients in Iran was significantly low. Therefore, the study highlights the importance of strengthening efforts to undertake necessary investigations in order to provide adequate health insurance, extensive and affordable welfare services, and more appropriate social and mental supports in order to improve the quality of life of the individuals with HIV/AIDS in Iran.

中文翻译：

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伊朗 HIV/AIDS 患者的生活质量：系统评价和荟萃分析

背景：评估 HIV/AIDS 患者的生活质量不仅对于评估疾病的影响非常重要，而且对于衡量干预措施的影响以提高他们在临床研究中的生活质量具有重要意义。因此，本研究旨在系统评价伊朗 HIV/AIDS 患者的生活质量。方法：在这项系统评价和荟萃分析中，使用相关关键词链于 1987 年 1 月 1 日至 2019 年 4 月 30 日在 PubMed、Scopus、Web of Science、Embase、伊朗科学信息数据库 (SID) 和马吉兰。此外，对重点期刊和灰色文献进行了手动检索。Meta分析由CMA2软件进行。结果：在检索到的 1576 条记录中，有 8 项研究符合纳入标准。患者的平均年龄为 37.15 ± 9.46 岁。敏感性分析前后生活质量的平均得分为（39.13 [28.36–49.901 95% CI P>0.000] vs. 49.05 [46.31–51.79 95% CI P>0.000]）。此外，与单身患者相比，已婚患者的生活质量平均得分分别为38.86±3.83和40±6.37，就业和失业状态分别为56.33±4.67和43.64±1.94。虽然生活质量是根据教育水平来衡量的，但小学与学历教育的得分分别为 29.59±9.34 和 41.65±4.45。结论：伊朗HIV/AIDS患者的QOL评分显着偏低。因此，该研究强调了加强努力进行必要调查以提供足够的健康保险的重要性，