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The association between neurocognitive functioning and clinical features of borderline personality disorder
Brazilian Journal of Psychiatry ( IF 5.5 ) Pub Date : 2020-10-01 , DOI: 10.1590/1516-4446-2019-0752
Bahar Kaplan 1 , Medine Yazici Gulec 2 , Sakir Gica 3 , Huseyin Gulec 2
Affiliation  

Objective: To investigate the relationship between neurocognitive profiles and clinical manifestations of borderline personality disorder (BPD). Methods: Forty-five patients diagnosed with BPD and 35 healthy volunteers were included in the study. The BPD group was evaluated with the Borderline Personality Inventory for dissociative, impulsivity and suicidal dimensions. The Verbal Memory Processes Test and the Cambridge Neurophysiological Assessment Battery were administered to both the BPD and healthy control groups. Results: BPD patients differed from controls in sustained attention, facial emotion recognition, and deteriorated verbal memory function. A model consisting of the Dissociative Experiences Scale – Taxon (DES-T), motor impulsivity and Scale for Suicidal Behavior scores explained 52% of the variance in Borderline Personality Inventory scores. It was detected that motor impulsivity, decision-making and recognizing sadness may significantly predict DES-T scores, and response inhibition and facial emotion recognition scores may significantly predict impulsivity. Conclusion: Our findings demonstrate that the disassociation, impulsivity, and suicidality dimensions are sufficient to represent the clinical manifestations of BPD, that they are related to neurocognitive differences, and that they interact with clinical features.

中文翻译:

边缘型人格障碍的神经认知功能与临床特征的关系

目的:探讨边缘型人格障碍(BPD)的神经认知特征与临床表现之间的关系。方法:本研究包括 45 名诊断为 BPD 的患者和 35 名健康志愿者。BPD 组使用边缘人格量表评估分离性、冲动性和自杀性维度。语言记忆过程测试和剑桥神经生理学评估组被管理到 BPD 和健康对照组。结果:BPD 患者在持续注意力、面部情绪识别和语言记忆功能恶化方面与对照组不同。一个由分离体验量表 - 分类单元 (DES-T) 组成的模型,运动冲动性和自杀行为量表评分解释了边缘人格量表评分中 52% 的差异。检测到运动冲动、决策和识别悲伤可能显着预测DES-T分数,反应抑制和面部情绪识别分数可能显着预测冲动。结论:我们的研究结果表明,分离、冲动和自杀维度足以代表 BPD 的临床表现,它们与神经认知差异有关,并且它们与临床特征相互作用。
更新日期:2020-10-01
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