The efficiency of using silicon nanoparticles, produced by laser ablation of porous silicon in liquids, as agents for hyperthermia of tumours using laser radiation with wavelengths of 633 and 800 nm is evaluated. Using the optical parameters of the nanoparticles suspensions determined earlier by the spectrophotometry measurements, the heating of tumour tissue with embedded nanoparticles is numerically modelled. The heat transfer equation is solved by the finite element method which considers the volumetric distribution of the absorbed light power, calculated by the Monte Carlo technique, as a distributed heat source. The simulations performed indicate that embedding silicon nanoparticles with a concentration of up to 5 mg mL⁻¹ into a tumour allows its maximum temperature to be increased by 0.2–4 C in comparison with heating the tumour without nanoparticles depending on the irradiation wavelength and intensity.

评估了通过使用激光消融液体中的多孔硅产生的硅纳米颗粒作为使用波长为633和800 nm的激光辐射的肿瘤热疗剂的效率。使用先前通过分光光度法测量确定的纳米颗粒悬浮液的光学参数，对带有嵌入式纳米颗粒的肿瘤组织的加热进行了数值建模。传热方程通过有限元方法求解，该方法将通过蒙特卡洛技术计算的吸收光功率的体积分布视为分布式热源。进行的模拟表明，埋入浓度高达5 mg mL ^-1的硅纳米颗粒 与加热没有纳米颗粒的肿瘤相比，根据肿瘤的照射波长和强度，进入肿瘤会使其最高温度升高0.2–4C。