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Mesoporous TiO2-based architectures as promising sensing materials towards next-generation biosensing applications
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2020-12-10 , DOI: 10.1039/d0tb02292f
Fauzan Amri 1, 2, 3, 4, 5 , Ni Luh Wulan Septiani 1, 2, 3, 4, 5 , Muhammad Rezki 1, 2, 3, 4, 5 , Muhammad Iqbal 1, 2, 3, 4, 5 , Yusuke Yamauchi 6, 7, 8, 9, 10 , Dmitri Golberg 11, 12, 13, 14, 15 , Yusuf Valentino Kaneti 1, 2, 3, 4, 5 , Brian Yuliarto 1, 2, 3, 4, 5
Affiliation  

In the past two decades, mesoporous TiO2 has emerged as a promising material for biosensing applications. In particular, mesoporous TiO2 materials with uniform, well-organized pores and high surface areas typically exhibit superior biosensing performance, which includes high sensitivity, broad linear response, low detection limit, good reproducibility, and high specificity. Therefore, the development of biosensors based on mesoporous TiO2 has significantly intensified in recent years. In this review, the expansion and advancement of mesoporous TiO2-based biosensors for glucose detection, hydrogen peroxide detection, alpha-fetoprotein detection, immobilization of enzymes, proteins, and bacteria, cholesterol detection, pancreatic cancer detection, detection of DNA damage, kanamycin detection, hypoxanthine detection, and dichlorvos detection are summarized. Finally, the future perspective and research outlook on the utilization of mesoporous TiO2-based biosensors for the practical diagnosis of diseases and detection of hazardous substances are also given.

中文翻译:

基于介孔TiO2的体系结构可作为面向下一代生物传感应用的有前途的传感材料

在过去的二十年中,介孔TiO 2已经成为一种有前途的生物传感材料。特别地,具有均匀,组织良好的孔和高表面积的介孔TiO 2材料通常表现出优异的生物传感性能,包括高灵敏度,宽线性响应,低检测限,良好的再现性和高特异性。因此,近年来,基于介孔TiO 2的生物传感器的开发显着增强。本文综述了介孔TiO 2的扩展和发展基于葡萄糖的生物传感器,双氧水检测,甲胎蛋白检测,酶,蛋白质和细菌的固定化,胆固醇检测,胰腺癌检测,DNA损伤检测,卡那霉素检测,次黄嘌呤检测和敌敌畏检测。最后,给出了介孔TiO 2基生物传感器在疾病实际诊断和有害物质检测中的应用前景和研究前景。
更新日期:2021-01-06
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