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Recommended confidence intervals for the conditional odds ratio in matched-pairs designs
Journal of Biopharmaceutical Statistics ( IF 1.2 ) Pub Date : 2021-01-05 , DOI: 10.1080/10543406.2020.1858309
Chao Chen 1 , Wenchen Tan 1 , Zhigang Huang 1 , Jinlin Du 1 , Haibing Yu 1 , Haiyan Pan 1
Affiliation  

ABSTRACT

There has been limited research on the confidence intervals of the conditional odds ratio in matched-pairs design. This article investigates the interval estimation of the conditional odds ratio. We described several confidence intervals, which are available in some situations, and they can produce different results. We tried to determine which method(s) should be recommended for different situations. We derived four confidence intervals from the delta test, the score test, the inferential model test, and the fiducial test, and employed four exact calculation studies to compare the performances of the four methods, in order to make recommendations for small and moderate-to-large sample sizes. All of the methods are illustrated using a real example. And we offered the recommendations for different situations.



中文翻译:

配对设计中条件优势比的推荐置信区间

摘要

关于配对设计中条件优势比的置信区间的研究有限。本文研究了条件优势比的区间估计。我们描述了几个置信区间,它们在某些情况下可用,它们可以产生不同的结果。我们试图确定应针对不同情况推荐哪种方法。我们从 delta 检验、分数检验、推理模型检验和基准检验中推导出四个置信区间,并采用四个精确计算研究来比较四种方法的性能,以便为中小- 大样本量。所有的方法都使用一个真实的例子来说明。我们提供了针对不同情况的建议。

更新日期:2021-01-05
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