The formation of iodinated by-products during the chemical oxidation process for organic compounds contaminated water has gained increasing attention. Iodinated by-products are more genotoxic, cytotoxic and mutagenic than those of chlorine and bromine analogs. It was reported that the oxidation process of iodinated X-ray contrast media (ICM) could generate iodinated by-products. This study investigated the generation of iodinated by-products during catalytic ozonation of iohexol (one of wide detected ICM). The formation of iodoform (IF) and monoiodoacetic acid (MIAA), and the degradation kinetics of iohexol were compared in different oxidation systems. The effect of various factors, including the iohexol concentration, ozone concentration, HA concentration and solution pH on iodinated by-products generation was evaluated. Additionally, the fate of iodine was investigated by the mass balance calculation. The generated concentrations of I-THMs species with one iodide atom were far higher than those of species with more iodine atoms in the catalytic system at the coexistence of Cl⁻ and Br⁻. The generation of I-THMs in actual water was relatively low and the normalized value of I-THMs/DOC (μg/mg) had no significant difference. The formation mechanism of high molecular weight iodine-containing by-products included cleavage of the side chain, H-abstraction, substitution iodine for chlorine or bromine and amide oxidation.

在有机化合物污染的水的化学氧化过程中，碘化副产物的形成越来越受到关注。碘化副产物比氯和溴类似物具有更高的遗传毒性，细胞毒性和致突变性。据报道，碘化X射线造影剂（ICM）的氧化过程可能产生碘化副产物。这项研究调查了碘海醇（广泛检测到的ICM之一）催化臭氧氧化过程中碘化副产物的产生。比较了不同氧化体系下碘仿（IF）和一碘乙酸（MIAA）的形成以及碘海醇的降解动力学。评估了碘海醇浓度，臭氧浓度，HA浓度和溶液pH值等各种因素对碘代副产物生成的影响。另外，通过质量平衡计算研究了碘的命运。在Cl并存的情况下，带有一个碘原子的I-THMs物种的生成浓度远远高于具有碘原子的I-THMs物种的生成浓度。^-和Br ^-。实际水中I-THM的生成量相对较低，I-THMs / DOC的标准化值（μg/ mg）没有显着差异。高分子量含碘副产物的形成机理包括侧链的裂解，H的吸收，碘被氯或溴取代以及酰胺的氧化。