In this study, the phytochemical, phenolic, flavonoid and bioactive compounds were successfully screened from crude extract of Sargassum wightii by LC-MS analysis after NIST interpretation. Bacterial growth inhibition study result was shown with 24 mm zone inhibition at 200 µg/mL concentration against P. aeruginosa. The increased phenolic content was much closed to gallic acid and the range was observed at 250 μg/mL concentration. In addition, flavonoid contents of the algae extract was indicated more significant with rutin at 200 μg/mL. In result, both the phenolic and flavonoid contents of the extract were more correlated with gallic acid and rutin. Further, the total anti-oxidant and DPPH radical scavenging activities were shown increased activity at 200 μg/mL concentrations. Furthermore, the excellent anti-bacterial alteration result was observed at 200 μg/mL concentration by minimum inhibition concentration. Therefore, the result was revealed that the marine algae Sargassum wightii has excellent phytochemical and anti-oxidant activities, and it has improved anti-bacterial activity against P. aeruginosa.

在这项研究中，通过NIST解释后，通过LC-MS分析成功地从Wargari Sargassum wightii的粗提物中筛选出了植物化学成分，酚类，类黄酮和生物活性化合物。细菌生长抑制研究结果显示，以200μg/ mL的浓度对铜绿假单胞菌有24 mm的区域抑制作用。增加的酚含量与没食子酸非常接近，并且在250μg/ mL的浓度下观察到该范围。另外，藻类提取物的类黄酮含量显示为200μg/ mL的芦丁时更为显着。结果，提取物中的酚类和类黄酮含量与没食子酸和芦丁的相关性更高。此外，在200μg/ mL的浓度下，总的抗氧化剂和DPPH自由基清除活性显示出增加的活性。此外，以最小抑制浓度在200μg/ mL的浓度下观察到了优异的抗菌改变效果。因此，结果表明，海藻Sargassum wightii具有优异的植物化学和抗氧化活性，并且对铜绿假单胞菌具有改善的抗菌活性。。