This work represents the first reported effort to build an extensive database of the organic volatile and semi-volatile contaminants present in car dust as a result of migration from materials used in auto-manufacturing. Untargeted analysis of car dust samples has been performed using comprehensive two-dimensional gas chromatography combined with time-of-fight mass spectrometry (GC×GC ‒ToF MS) after generic sample preparation. The enhanced separation power and structural confirmation capabilities provided by this technique have been used for the either positive or tentative identification of 245 GC-amenable compounds, a number of them being identified for the first time in this type of matrix. Information concerning 5 compounds remaining unidentified has also been provided. Results have been summarised in a searchable database containing chromatographic, mass spectral and normalised abundances calculated for the detected analytes in the ten investigated car dusts used to discuss the main findings of the study. Results are expected to serve other researcher to take decisions concerning priority analytes for further evaluation in this research field and for car manufacturers who might search for safer materials.

这项工作是首次报道的工作，目的是建立广泛的数据库，以存储由于汽车制造中的材料迁移而产生的汽车灰尘中有机挥发性和半挥发性污染物。通用样品制备后，使用全面的二维气相色谱结合飞行时间质谱（GC×GC GCToF MS）对汽车粉尘样品进行了非目标分析。这项技术提供的增强的分离能力和结构确认能力已用于245种适合GC的化合物的阳性或初步鉴定，其中许多是首次在此类基质中鉴定。还提供了有关5种尚未确定的化合物的信息。结果已汇总在一个可搜索的数据库中，该数据库包含色谱，质谱图和归一化的丰度，该丰度是对十个用于调查研究的主要发现的被调查汽车尘埃中检测到的分析物进行计算得出的。预期结果将有助于其他研究人员做出有关优先分析物的决定，以便在该研究领域中进行进一步评估，并为可能寻求更安全材料的汽车制造商提供决策。