Objective

To evaluate the influence of vitamin D supplementation with a multimodal exercise program on postural balance and muscle strength in older women with low bone mineral density (BMD) and vitamin D insufficiency.

Methods

12-week, randomized, double-blind, placebo-controlled clinical trial. Total of 422 subjects were screened for participation, and 46 met the inclusion criteria. Those were randomized into an experimental group (EG; n = 23) and control group (CG; n = 23). At the time of enrollment, all subjects had low BMD, vitamin D insufficiency, and were not practicing resistance exercise. Muscle strength assessments were performed by the 30-s sit to stand test; 15-steps climbing test; handgrip dynamometer and knee muscle strength using an isokinetic dynamometer at 60°/sec. Postural balance was clinically evaluated by the MiniBESTest and by a force platform. Dynamic balance was assessed by standing up from a chair and walk over a step, using also a force platform.

Results

In the EG, vitamin D levels increased in the post-treatment period (P < 0.001) whereas in CG levels remained unchanged (P = 0.86). Both groups improved muscular strength in the dynamometry isokinetic test: flexors PT/BW – right (P < 0.02) and left side (P < 0.04). In the dynamic postural balance during the task to step up over: the Lift Up Left was better in the CG (P = 0.01); the Moment Time left was better in the CG (P = 0.01); the Impact index left was better in the EG (P = 0.01). The Mini-BESTest - both groups improved the postural balance test (P < 0.001).

Conclusion

Vitamin D supplementation associated with multimodal exercise program did not augment muscle strength adaptation or postural balance in older women with low bone mineral density and vitamin D insufficiency.

中文翻译：

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低骨矿物质密度的老年女性补充维生素D与12周多式联运训练：一项随机双盲安慰剂对照试验

目的

为了评估补充维生素D的多模式运动计划对低骨密度（BMD）和维生素D功能不足的老年妇女的姿势平衡和肌肉力量的影响。

方法

12周，随机，双盲，安慰剂对照的临床试验。共筛选了422名受试者，其中46名符合纳入标准。将它们随机分为实验组（EG；n  = 23）和对照组（CG； n = 23）。在入组时，所有受试者的BMD，维生素D功能不足且未进行抵抗运动。肌肉力量评估通过静坐试验30秒钟进行；15步爬升测试；使用等速测功机以60°/ sec的速度进行测功机和膝盖肌肉的力量测试。通过MiniBESTest和测力平台对姿势平衡进行了临床评估。动态平衡的评估是通过坐在椅子上站立并走一步，也使用一个测力平台。

结果

在EG中，维生素D水平在治疗后升高（P  <0.001），而在CG水平则保持不变（P  = 0.86）。两组在测功动力学测试中均提高了肌肉强度：屈肌PT / BW –右（P  <0.02）和左（P  <0.04）。在任务完成过程中的动态姿势平衡中：CG上的向左抬起效果更好（P  = 0.01）；CG剩下的瞬间时间更好（P = 0.01）；在EG中留下的影响指数更好（P = 0.01）。Mini-BESTest-两组均改善了姿势平衡测试（P  <0.001）。

结论

与多模式运动计划相关的维生素D补充剂并没有增强骨矿物质密度低和维生素D功能不足的老年妇女的肌肉力量适应性或姿势平衡。