Microalgae have attracted significant interest worldwide as a prospective biofuel feedstock. Currently, biodiesel potential of microalgae has been confined at lab scale; however, economic feasibility is a limiting factor for commercialization. Thus, development of large-scale production system is an essential element to assess economic feasibility as well as policy support needed to implement large-scale production. To answer this, Dunaliella tertiolecta was selected for biodiesel feedstock production among other isolates, having 1.244 g/L dry biomass yield and 37%w/w lipid content. Operational cost of biodiesel production was 3.19 USD/L for lab scale which can be reduced to 0.77 USD/L at large-scale production by integrated and efficient resource utilization, namely, natural seawater (NSW), as growth media and unproductive coastland for production site. Capital investment of USD 82019.89 was calculated for biodiesel production facility with 16.7 KL annual production for one-hectare unproductive land. Economic evaluation of 10 years of production resulted into net present value (NPV) of USD 750.91 and 5.18% internal rate of return (IRR). Capital recovery can be achieved in 7.76 years as per normal payback analysis. Additionally, NPV can be increased to USD 30355 by upscaling production to five times with 50% more biomass productivity that would result into 14.23% IRR. Efficient resource integration, multiple products and co-products with market linkages, and appropriate policy facilitation are key factors for commercial viability of microalgae biodiesel production.

微藻作为一种潜在的生物燃料原料已经引起了全世界的广泛关注。目前，微藻的生物柴油潜力已经局限于实验室规模。但是，经济可行性是商业化的限制因素。因此，开发大规模生产系统是评估经济可行性以及实施大规模生产所需的政策支持的基本要素。为了回答这个问题，杜氏盐藻除其他分离菌外，该菌还用于生产生物柴油原料，其干生物质产量为1.244 g / L，脂质含量为37％w / w。实验室规模的生物柴油生产的运营成本为3.19美元/升，通过整合和有效利用资源（即天然海水（NSW））作为生长介质和非生产性沿海生产基地，大规模生产时可降低至0.77美元/升现场。计算出的生物柴油生产设施的资本投资为82019.89美元，一公顷非生产性土地的年产量为16.7 KL。对10年生产的经济评估得出净现值（NPV）为750.91美元，内部收益率（IRR）为5.18％。根据正常的投资回收期分析，资本回收可以在7.76年内实现。另外，通过将产量提升到五倍，生物量生产率提高50％，可以将NPV提升至30355美元，从而使内部收益率达到14.23％。有效的资源整合，具有市场联系的多种产品和副产品以及适当的政策便利化是微藻生物柴油生产商业可行性的关键因素。