HIV testing/counseling is a critical point during which non-clinical staff could intervene, discuss and/or refer clients for pre-exposure prophylaxis (PrEP). This analysis investigated the contextual factors affecting PrEP implementation within HIV testing sites. Two generalized linear mixed models were conducted to estimate PrEP implementation as a function of constructs from the Consolidated Framework for Implementation Research (CFIR). Qualitative interviews were analyzed thematically. Data integration occurred via joint analysis and triangulation. Constructs from the CFIR domain Characteristics of Individuals did not predict PrEP implementation when controlling for demographic characteristics; qualitative data signaled divergent findings in PrEP knowledge. Within the CFIR domains Inner and Outer Settings, relevant priority and available resources predicted PrEP implementation; qualitative data confirmed the importance of available resources and provided insight into the impact of cosmopolitanism and leadership. Addressing the contextual factors that affect PrEP implementation may help HIV testing staff to better implement PrEP programs.

HIV 检测/咨询是非临床工作人员可以干预、讨论和/或转介客户进行暴露前预防 (PrEP) 的关键点。该分析调查了影响 HIV 检测站点内 PrEP 实施的背景因素。进行了两个广义线性混合模型来估计 PrEP 实施作为实施研究综合框架 (CFIR) 的构造函数。定性访谈进行了主题分析。通过联合分析和三角测量进行数据整合。在控制人口特征时，来自个人的 CFIR 域特征的构造并不能预测 PrEP 的实施；定性数据表明 PrEP 知识的不同发现。在 CFIR 域内部和外部设置中，预测 PrEP 实施的相关优先事项和可用资源；定性数据证实了可用资源的重要性，并提供了对世界主义和领导力影响的洞察力。解决影响 PrEP 实施的背景因素可能有助于 HIV 检测人员更好地实施 PrEP 计划。