Dual Rh(II)/Pd(0) Relay Catalysis for One‐Pot Synthesis of α‐Quaternary Allylated Indolin‐2‐ones and Benzofuran‐2‐ones,Bulletin of the Korean Chemical Society

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Dual Rh(II)/Pd(0) Relay Catalysis for One‐Pot Synthesis of α‐Quaternary Allylated Indolin‐2‐ones and Benzofuran‐2‐ones
Bulletin of the Korean Chemical Society ( IF 2.3 ) Pub Date : 2021-01-04 , DOI: 10.1002/bkcs.12211
Yu Lim Lee ₁ , Kyu Ree Lee ₁ , Zi Xuan ₂ , Sang‐gi Lee ₁

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Cooperative Rh(II) and Pd(0) dual relay catalysis has been developed, which allowed one‐pot synthesis of α‐quaternary allylated indolin‐2‐ones and benzofuran‐2‐ones. The catalytic reaction proceeded through the sequential Rh(II)‐catalyzed intramolecular aromatic C(sp²)‐H bond functionalization of α‐diazo carbonyl compounds, followed by Pd(0)‐catalyzed allylic alkylation with allylic carbonates to afford the products in high yields (up to 97%).

中文翻译：

双Rh（II）/ Pd（0）中继催化用于一锅法合成α-季烷基化的吲哚啉-2-酮和苯并呋喃-2-酮

已经开发了合作的Rh（II）和Pd（0）双中继催化，可以一锅合成α-季烷基烯丙基化的吲哚-2-酮和苯并呋喃-2-酮。催化反应通过依次进行Rh（II）催化的α-重氮羰基化合物的分子内芳族C（sp ²）-H键的官能化反应，然后进行Pd（0）催化的烯丙基碳酸酯的烯丙基烷基化反应，从而得到高纯度的产物。产量（高达97％）。

更新日期：2021-01-04

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