Cystic echinococcosis (CE) is a severe zoonosis, caused by the larval stage of the tapeworm Echinococcus granulosus. This helminth infection is of increasing public health and socio-economic concern due to the considerable morbidity rates that cause economic losses both in the public health sector and in the livestock industry. Control programmes against E. granulosus are considered long-term actions which require an integrated approach and high expenditure of time and financial resources. Since 2010, an integrated approach to control CE has been implemented in a highly endemic area of continental southern Italy (Campania region). Innovative procedures and tools have been developed and exploited during the control programme based on the following strategies: i) active and passive surveillance in livestock (using geospatial tools for georeferencing), ii) diagnosis in dogs (using the FLOTAC techniques and molecular analysis), iii) targeted treatment of farm dogs (using purpose-built confinement cages), iv) early diagnosis in livestock (by ultrasonography), v) surveillance in humans (through hospital discharge records analysis), vi) monitoring the food chain (analysing raw vegetables), vii) outreach activities to the general public (through dissemination material, e.g. brochures, gadgets, videos, virtual reality). Over eight years, the integrated approach and the new strategies developed have resulted in a noteworthy reduction of the parasite infection rates in livestock (e.g. up to 30 % in sheep). The results obtained so far highlight that using a one health multidisciplinary and multi-institution effort is of pivotal importance in preparing CE control programmes at regional level and could be extended to other endemic Mediterranean areas.

囊性棘球蚴病 (CE) 是一种严重的人畜共患病，由细粒棘球绦虫的幼虫阶段引起。由于发病率很高，导致公共卫生部门和畜牧业的经济损失，这种蠕虫感染引起了越来越多的公共卫生和社会经济关注。针对E. granulosus 的控制程序被视为需要综合方法和大量时间和财政资源的长期行动。自 2010 年以来，在意大利南部大陆（坎帕尼亚地区）的高度流行地区实施了控制 CE 的综合方法。在基于以下策略的控制计划中开发和利用了创新程序和工具：i) 家畜的主动和被动监视（使用地理空间工具进行地理配准），ii）犬的诊断（使用 FLOTAC 技术和分子分析）， iii) 对农场犬进行针对性治疗（使用专用的禁闭笼），iv） 家畜的早期诊断（通过超声检查），v） 人类监测（通过出院记录分析），vi） 监测食物链（分析生蔬菜） ), vii) 面向公众的外展活动（通过传播材料，例如小册子、小工具、视频、虚拟现实）。八年来，综合方法和开发的新策略显着降低了牲畜的寄生虫感染率（例如，绵羊的寄生虫感染率高达 30%）。迄今为止获得的结果强调，使用一个卫生多学科和多机构的努力对于在区域一级准备 CE 控制计划至关重要，并且可以扩展到其他地中海流行地区。