Inspired by the feeding mechanisms of a nematode, a novel two-indenter (2I) micro-pump is analyzed theoretically for transport and mixing of a non-Newtonian fluid for the purpose of lab-on-a-chip applications. Considering that the viscous forces dominate the flows in microscopic regime, the concept lubrication theory was adopted to device the two-dimensional flow model of the problem. By approximating the movements of the indenter as a sinusoidal function, the details of the flow were investigated for variations in—frequency of contraction of the first value keeping the second valve at higher occlusion, and occlusion. The study indicates that occlusive nature of the second valve leads to the large pressure barrier which prevents the fluid to enter into the neighboring compartment. Transport occurs as the lumen opens to develop a suction pressure. Pressure barrier is found to be highest for dilatants followed by Newtonian and pseudo-plastics. Shear stress dependency on frequency the contraction of the first value is highest for lower values of flow behavior index. In conclusion, the study provides details connecting the flows resulting from the indentation of the front-end indenter to the frequency of indentation, geometry and rheology of the fluid, thus facilitating optimal design of the micro-pumps.

中文翻译：

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一种用于芯片实验室应用的新型基于双压头的微型泵：对非牛顿流体的流动进行建模和表征

受线虫喂食机制的启发，从理论上分析了一种新型双压头 (2I) 微型泵，用于非牛顿流体的传输和混合，用于芯片实验室应用。考虑到粘性力在微观状态下主导流动，采用概念润滑理论来装置问题的二维流动模型。通过将压头的运动近似为正弦函数，研究了流动细节的变化——第一个值的收缩频率，保持第二个阀门处于更高的闭塞状态，以及闭塞。研究表明，第二个阀门的闭塞特性导致了大的压力屏障，阻止了流体进入相邻的隔间。当管腔打开以产生抽吸压力时发生运输。发现膨胀剂的压力屏障最高，其次是牛顿和假塑料。剪切应力对频率的依赖性对于较低的流动行为指数值，第一个值的收缩是最高的。总之，该研究提供了将前端压头压痕产生的流动与流体的压痕频率、几何形状和流变学联系起来的详细信息，从而促进了微型泵的优化设计。