Herbicide-tolerant winter oilseed rape (OSR) varieties offer the opportunity of using imazamox for weed control, an active ingredient belonging to the chemical group of acetolactate synthase (ALS-) inhibitors. However, ALS inhibitors are used in many different crops and are the most resistance-prone herbicide mode of action. Their frequent application in a crop rotation increases the selection pressure for ALS herbicide resistance in weeds, which has to be considered when designing resistance management strategies. Alopecurus myosuroides Huds. is a frequent and economically important grass weed in Northwestern Europe, which has evolved resistance to several herbicide modes of action. For the sustainable use of herbicide-tolerant OSR varieties, studies on the effects of the different intensities of ALS inhibitor use on A. myosuroides population dynamics and resistance development are required. Two field trials were conducted including susceptible and multiple resistant A. myosuroides individuals and four weed control strategies varying in their intensity of ALS inhibitor use over a three-year trial period. A. myosuroides head numbers, the presence of target-site mutations in surviving plants, and crop yields were assessed annually, and the amount of A. myosuroides seeds in the soil seed bank was determined at the end of the trial period. The results show that the intensity of ALS inhibitor use significantly influenced the density of A. myosuroides and the development of resistance. Under weed control strategy IV (no ALS inhibitors), an increase in A. myosuroides head number was observed due to multiple resistance in the A. myosuroides population employed in the field trial. None of the four weed control strategies was able to control A. myosuroides infestation to an acceptable level. The results on A. myosuroides densities in the soil seed bank were highly variable and inconsistent. Molecular analysis of surviving plants showed a selection of ALS-resistant biotypes depending on the ALS inhibitor selection pressure. This study did not reveal any specific deterioration of A. myosuroides infestation associated with the use of imidazolinone-tolerant OSR in a short-term crop rotation. However, this OSR production system should not be employed if ALS-resistant A. myosuroides plants are present in the field.

耐除草剂的冬季油菜（OSR）品种提供了使用咪唑胺进行杂草控制的机会，杂草是一种活性成分，属于乙酰乳酸合酶（ALS-）抑制剂的化学类别。但是，ALS抑制剂被用于许多不同的农作物，并且是最易产生耐药性的除草剂作用方式。它们在作物轮作中的频繁应用增加了杂草中ALS除草剂抗性的选择压力，这在设计抗性管理策略时必须加以考虑。斑鸠草哈兹 是在西北欧常见且具有重要经济意义的草类杂草，它已经进化出对几种除草剂作用方式的抗性。为了可持续地使用耐除草剂的OSR品种，需要研究不同强度的ALS抑制剂的使用对鼠李糖单胞菌种群动态和抗性发展的影响。进行了两项田间试验，包括易感性和多重抗药性芥子气单胞菌个体和四种杂草控制策略，这些策略在三年的试用期内因其对ALS抑制剂的使用强度而异。每年评估A. myosuroides的头数，存活植物中靶位点突变的存在以及农作物的产量，以及A. myosuroides的量在试验期结束时确定土壤种子库中的种子。结果表明，ALS抑制剂的使用强度显着影响了神经节律杆菌的密度和抗药性的发展。在杂草控制策略IV（无ALS抑制剂）下，由于在田间试验中使用的A. myosuroides种群具有多重抗性，因此观察到A. myosuroides头数增加。四种杂草控制策略均不能将Myosuroides的侵染控制在可接受的水平。肌硫曲霉的结果土壤种子库中的密度变化很大且不一致。存活植物的分子分析表明，取决于ALS抑制剂选择压力，可以选择ALS抗性生物型。这项研究没有揭示在短期作物轮作中与耐咪唑啉酮OSR的使用有关的神经硫曲霉侵袭的任何特定恶化。但是，如果野外存在耐ALS的A. myosuroides植物，则不应使用此OSR生产系统。