Shijiazhuang is one of the cities in the North China Plain. In recent decades, this city has experienced high levels of fine particulate matter (PM_2.5), which have potentially significant effects on human health. In this study, the health effects of PM_2.5 exposure in Shijiazhuang were estimated by applying an integrated exposure-response model. Premature mortality, years of life lost (YLL), and the mortality benefits linked to reduced levels of PM_2.5 were quantified for the period 2015–2017. In 2015, 2016, and 2017, cerebrovascular diseases caused the highest premature mortality (2432, 2449, and 2483, respectively), followed by ischemic heart diseases (1391, 1479, and 1493, respectively), lung cancer (639, 660, and 639, respectively), and chronic obstructive pulmonary diseases (533, 519, and 473, respectively). Notably, the total number of premature deaths caused by PM_2.5 exposure in Shijiazhuang in 2015, 2016, and 2017 were 4994, 5107, and 5088, respectively. Moreover, the YLL in the same years were 47001, 47880 and 47381, respectively. Interestingly, the YLL per 1000 females was lower than that per 1000 males. Finally, we noted that premature mortality and YLL decreased by 84.2% and 84.6% when the PM_2.5 levels diminished to 10 µg/m³. Overall, the results of this study improve our understanding of how high PM_2.5 concentrations affect human health and suggest the application of more stringent measures in Shijiazhuang to alleviate the associated health risks.

石家庄是华北平原的城市之一。近几十年来，这座城市经历了高水平的细颗粒物（PM _2.5），这可能对人类健康产生重大影响。在这项研究中，通过应用综合暴露-反应模型估算了石家庄PM _2.5暴露对健康的影响。过早的死亡率，丧失的生命年（YLL）以及与降低的PM _2.5水平相关的死亡率收益对2015-2017年期间进行了量化。在2015年，2016年和2017年，脑血管疾病导致最高的过早死亡（分别为2432、2449和2483），其次是缺血性心脏病（分别为1391、1479和1493），肺癌（639、660和分别为639和慢性阻塞性肺疾病（分别为533、519和473）。值得注意的是，石家庄2015年，2016年和2017年因PM _2.5暴露引起的过早死亡总数分别为4994、5107和5088。此外，同年的YLL分别为47001、47880和47381。有趣的是，每千名女性的YLL低于每千名男性的YLL。最后，我们注意到PM _2.5可使早产儿死亡率和YLL分别降低84.2％和84.6％浓度降至10 µg / m ³。总体而言，这项研究的结果增进了我们对高PM _2.5浓度如何影响人类健康的理解，并建议在石家庄采取更严格的措施来减轻相关的健康风险。