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Sodium bicarbonate therapy for acute respiratory acidosis.
Current Opinion in Nephrology and Hypertension ( IF 2.2 ) Pub Date : 2020-12-31 , DOI: 10.1097/mnh.0000000000000687
Ranjeeta Chand 1 , Erik R Swenson 2 , David S Goldfarb 1
Affiliation  

Respiratory acidosis is commonly present in patients with respiratory failure. The usual treatment of hypercapnia is to increase ventilation. During the recent surge of COVID-19, respiratory acidosis unresponsive to increased mechanical ventilatory support was common. Increasing mechanical ventilation comes at the expense of barotrauma and hemodynamic compromise from increasing positive end-expiratory pressures or minute ventilation. Treating acute respiratory acidemia with sodium bicarbonate remains controversial.

中文翻译:

碳酸氢钠治疗急性呼吸性酸中毒。

呼吸性酸中毒常见于呼吸衰竭患者。高碳酸血症的通常治疗是增加通气。在最近 COVID-19 激增期间,对增加机械通气支持无反应的呼吸性酸中毒很常见。增加机械通气的代价是气压伤和因增加呼气末正压或每分钟通气量而导致的血流动力学损害。用碳酸氢钠治疗急性呼吸性酸血症仍存在争议。
更新日期:2021-01-06
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