Fibromyalgia (FM) is a lifelong central nervous system disorder that is precipitated by a range of biological, psycho-cognitive, and social factors. The aims of this exploratory study were to (a) identify biopsychosocial and cognitive factors that may affect an individual’s response to FM, (b) determine whether individuals with FM can be grouped into homogeneous subgroups based on biopsychosocial factors associated with response to FM, and (c) compare subgroup differences in health outcomes and life satisfaction. This study included 302 participants with FM. Principal components analysis yielded three sets of biopsychosocial factors that may affect response to FM (i.e., protective, cognitive-affective, and physical factors). Based on these three factors, a cluster analysis was performed, which produced three homogeneous subgroups: (a) the moderate amount of problems group, (b) the least amount of problems group, and (c) the many problems group. Analysis of variance (ANOVA) results indicated that these three subgroups differed significantly in terms of health outcomes and life satisfaction. The findings of this study broaden the existing literature related to understanding FM from a multidimensional symptom response perspective and contribute to the development and validation of biopsychosocial interventions for people with FM.

中文翻译：

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适应纤维肌痛的生物心理社会因素的实证分类法：多变量分析的结果

纤维肌痛 (FM) 是一种终生的中枢神经系统疾病，由一系列生物、心理认知和社会因素诱发。这项探索性研究的目的是 (a) 确定可能影响个人对 FM 反应的生物心理社会和认知因素，(b) 确定是否可以根据与 FM 反应相关的生物心理社会因素将 FM 个体分为同质亚组，以及(c) 比较亚组在健康结果和生活满意度方面的差异。这项研究包括 302 名 FM 参与者。主成分分析产生了三组可能影响对 FM 反应的生物心理社会因素（即保护性、认知情感和身体因素）。基于这三个因素，进行了聚类分析，产生了三个同质亚组：(a) 中等问题组，(b) 最少问题组，以及 (c) 多问题组。方差分析 (ANOVA) 结果表明，这三个亚组在健康结果和生活满意度方面存在显着差异。本研究的结果拓宽了与从多维症状反应角度理解 FM 相关的现有文献，并有助于开发和验证针对 FM 患者的生物心理社会干预措施。