Abstract:Depressive symptoms, somatic complaints, and circulating levels of inflammatory biomarkers interleukin-6 (IL-6) and C-reactive protein (CRP) were examined as correlates of social and physical peer victimization in an ethnically diverse sample of adolescents (N = 91) using a multi-informant approach. Hierarchical regression analyses indicated that social peer victimization was associated with higher levels of depressive symptoms, somatic complaints, and inflammation. However, being physically bullied only predicted lower levels of inflammatory markers. Additionally, the role of depressive symptoms in the victimization– inflammation relation was examined. Social victimization indirectly influenced levels of IL-6 (via depressive symptoms) and CRP (via depressive symptoms and IL-6, in series). These results provide initial evidence that peer victimization is associated with inflammatory markers in an adolescent sample and that symptoms of depression may be an important presage to inflammation and health problems, while highlighting the differential effects of social and physical forms of peer victimization.

中文翻译：

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社会和身体同伴受害对青少年系统性炎症的影响

摘要：在不同种族的青少年样本中，抑郁症状，躯体主诉以及炎症生物标志物白细胞介素6（IL-6）和C反应蛋白（CRP）的循环水平被检查为社会和身体同伴受害的相关因素（N = 91）使用多信息方法。层次回归分析表明，社交同伴受害与抑郁症状，躯体主诉和炎症程度较高有关。但是，被人欺负只会预示着较低的炎症标记物水平。此外，还研究了抑郁症状在受害与炎症关系中的作用。社会受害间接影响了IL-6（通过抑郁症状）和CRP（通过抑郁症状和IL-6，串联）的水平。