This article examines infrastructure and technology assembled to support a malaria vaccine clinical trial, conducted between 2009 and 2014. It draws on ethnographic fieldwork at a medical research centre in north-eastern Tanzania, with additional data from interviews with researchers, vaccine scientists and trial funders. The infrastructure and technology were conceived of as enabling the development of a vaccine and facilitating future medical research and health care provision in Tanzania. However, after the clinical trial ended, these material remains were decaying, repurposed or lacked long-term sustainability without continued research funding. For trial staff in Tanzania, this led to expressions of affect, including disappointment, ambivalence and frustration as expectations for the future were foreclosed. The author argues that the material remains of the clinical trial had varied impacts and, furthermore, ambivalence is an embedded part of clinical trials due to their time constraints and lack of local rooting. The end of this clinical trial exposes the limitations of global health research in bringing about lasting change to low-resource settings. This article highlights the need to consider the life of material objects after research concludes.

中文翻译：

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建立遗产？疟疾疫苗临床试验的歧义影响

本文研究了为支持疟疾疫苗临床试验而组建的基础设施和技术，该基础设施和技术在2009年至2014年之间进行。该研究借鉴了坦桑尼亚东北部医学研究中心的人种学实地调查工作，以及来自对研究人员，疫苗科学家和试验资助者的采访中获得的其他数据。该基础设施和技术被认为可以开发疫苗并促进坦桑尼亚未来的医学研究和保健提供。然而，在临床试验结束后，这些材料的残骸正在腐烂，被重新利用或缺乏长期的可持续性，而没有持续的研究经费。对于坦桑尼亚的审判人员来说，这导致了情感的表达，包括失望，矛盾和沮丧，因为人们对未来的期望被取消了。作者认为，临床试验的材料遗留物影响多种多样，而且，由于时间有限且缺乏本地根基，矛盾情绪是临床试验的一部分。该临床试验的结尾暴露了全球卫生研究在为资源贫乏地区带来持久变化方面的局限性。本文强调研究结束后必须考虑材料对象的寿命。