Objective: Mexican American (MA) children are more likely to grow up in poverty than their non-Hispanic/Latinx white peers and are at an elevated risk for early onset obesity. The current study evaluated the effects of prenatal family- and neighborhood-level disadvantage on children's weight and weight gain from 12 months through 4.5 years of age. Maternal breastfeeding duration was evaluated as a potential mechanism underlying the relation between multilevel disadvantage and weight. Methods: Data was collected from 322 low-income, MA mother-child dyads. Women reported the degree of family socioeconomic disadvantage and breastfeeding status. Neighborhood disadvantage was evaluated with census-level metrics. Children's weight and height were measured at laboratory visits. Results: Greater prenatal neighborhood disadvantage predicted higher child Body Mass Index (BMI) at 12 months, over and above family-level disadvantage; this effect remained stable through 4.5 years. Breastfeeding duration partially mediated the effect of neighborhood disadvantage on child BMI. Breastfeeding duration predicted child BMI at all timepoints. Conclusions: Maternal prenatal residence in a neighborhood with high concentrated disadvantage may place low-income, MA children at increased risk of elevated weight status during the first few years of life. Breastfeeding duration emerged as potentially modifiable pathway through which the prenatal neighborhood impacts children's early life weight. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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墨西哥裔美国人体重的产前社会经济多层次决定因素：母乳喂养的调节。

目的：与非西班牙裔/拉丁裔白人同龄人相比，墨西哥裔（MA）儿童更有可能在贫困中成长，并且罹患早期肥胖症的风险更高。当前的研究评估了产前家庭和邻里水平的不利因素对12个月至4.5岁儿童体重和体重增加的影响。母乳喂养持续时间被评估为潜在的多层次不利因素和体重之间关系的潜在机制。方法：从322个低收入的MA母亲儿童双胞胎中收集数据。妇女报告了家庭社会经济不利程度和母乳喂养状况。邻里劣势是通过普查级指标进行评估的。在实验室就诊时测量儿童的体重和身高。结果：更大的产前邻里劣势预示着12个月的儿童身体质量指数（BMI）会高于家庭水平的劣势；这种效果在4.5年内一直保持稳定。母乳喂养的时间部分介导了邻里不利对儿童BMI的影响。母乳喂养的持续时间可在所有时间点预测儿童的BMI。结论：产前居住在高集中度弱势社区的孕妇可能会使低收入的MA儿童在生命的最初几年中体重增加的风险增加。母乳喂养的持续时间已成为可能改变的途径，通过该途径，产前邻里会影响儿童的早期生活体重。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。这种效果在4.5年内一直保持稳定。母乳喂养的时间部分介导了邻里不利对儿童BMI的影响。母乳喂养的持续时间可在所有时间点预测儿童的BMI。结论：产前居住在高集中度弱势社区的孕妇可能会使低收入的MA儿童在生命的最初几年中体重增加的风险增加。母乳喂养的持续时间已成为可能改变的途径，通过该途径，产前邻里会影响儿童的早期生活体重。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。这种效果在4.5年内一直保持稳定。母乳喂养的时间部分介导了邻里不利对儿童BMI的影响。母乳喂养的持续时间可在所有时间点预测儿童的BMI。结论：产前居住在高集中度弱势社区的孕妇可能会使低收入的MA儿童在生命的最初几年中体重增加的风险增加。母乳喂养的持续时间已成为可能改变的途径，通过该途径，产前邻里会影响儿童的早期生活体重。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。产前居住在高集中度弱势社区的孕妇可能会使低收入的MA儿童在生命的最初几年中体重增加的风险增加。母乳喂养的持续时间已成为可能改变的途径，通过该途径，产前邻里会影响儿童的早期生活体重。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。产前居住在高集中度弱势社区的孕妇可能会使低收入的MA儿童在生命的最初几年中体重增加的风险增加。母乳喂养的持续时间已成为可能改变的途径，通过该途径，产前邻里会影响儿童的早期生活体重。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。