This special issue showcases how investigators working in different areas of health behavior change are utilizing early phase studies to advance intervention development. Through the publication of design or protocol papers for currently funded Science of Behavior Change (SOBC) network projects, the special issue illustrates how investigative teams are implementing the experimental medicine approach to advance our understanding of the mechanisms of action that underlie behavior change interventions and, in turn, develop an evidence base that can inform future intervention design. Given that a goal of the experimental medicine approach is the accumulation of an evidence base regarding the links between intervention strategies and putative mechanisms of action, it is critical that this evidence base is readily accessible to investigators and practitioners. Therefore, each of the included articles describes how it is implementing the open-science approach within its study protocol to ensure rigor and reproducibility. Each article provides information about how to register an early phase experiment before study conduct and how to publicly deposit the data, metadata, and publications. The special issue includes 10 design and protocol articles and 2 commentaries on a diverse array of scientific areas and approaches to test mechanisms of action for health behavior change interventions. By disseminating how the National Institutes of Health SOBC Initiative has supported the conduct of early phase intervention studies implementing the experimental medicine and open science approaches, the special issue provides a substantive roadmap to other scientists for how to adopt these approaches. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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使用早期研究推进干预研究：行为改变的科学。

本期特刊展示了在健康行为变化的不同领域工作的研究人员如何利用早期研究来促进干预措施的发展。通过为当前资助的行为改变科学（SOBC）网络项目发布设计或协议文件，该特刊说明了研究团队如何实施实验医学方法，以加深我们对行为改变干预基础的作用机制的理解，以及反过来，建立可以为将来的干预设计提供依据的证据基础。鉴于实验医学方法的目标是积累有关干预策略与假定作用机制之间联系的证据基础，至关重要的是，调查人员和从业人员应易于获得该证据基础。因此，所包括的每篇文章都描述了如何在其研究方案内实施开放科学方法，以确保严谨性和可重复性。每篇文章均提供有关如何在进行研究之前注册早期实验以及如何公开存储数据，元数据和出版物的信息。本期特刊包括10篇设计和规程文章，以及2篇评论，涉及各种科学领域和方法，以测试针对健康行为改变干预措施的作用机制。通过传播美国国立卫生研究院SOBC倡议如何支持进行早期干预研究以实施实验医学和开放科学方法，特刊为其他科学家提供了如何采用这些方法的实质性路线图。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。