It is commonly believed that proven abnormalities in the structure and functioning of the prefrontal lobes affect cognitive deficits in children with ADHD. The purpose of the current study was to assess vigilance, inhibitory control, and regional cerebral blood oxygenation (rCBO2) in the prefrontal cortex (PFC) of children with ADHD. The study included 150 children with ADHD and 51 typically developing (TD) children aged 9-12 years. Children with ADHD showed a deficit in vigilance (assessed by the shortened version of the Mackworth clock task), inhibitory control (the Stroop task), different rCBO2 patterns in the PFC, as well as lower cortical activation during cognitive tasks. These differences are discussed in the context of the types of ADHD presentations.

中文翻译：

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PFC 中的警惕性、抑制性控制和局部脑血氧合 - ADHD 表现类型的差异


人们普遍认为，已证实的前额叶结构和功能异常会影响多动症儿童的认知缺陷。本研究的目的是评估 ADHD 儿童前额皮质 (PFC) 的警觉性、抑制控制力和局部脑血氧合 (rCBO2)。该研究包括 150 名 ADHD 儿童和 51 名 9-12 岁的典型发育 (TD) 儿童。患有多动症的儿童表现出警惕性（通过缩短版的麦克沃斯时钟任务评估）、抑制控制（斯特鲁普任务）、前额叶皮层中不同的 rCBO2 模式以及认知任务期间皮层激活较低的缺陷。这些差异是在多动症表现类型的背景下讨论的。