ABSTRACT

Introduction: Juvenile idiopathic arthritis (JIA) is the most common rheumatic inflammatory condition in childhood. The long-term morbidity, mortality, and quality of life have improved with the earlier use of disease-modifying drugs (DMARDs) and the availability of biology disease-modifying drugs (bDMARDs). Despite the improvement of treatment, around 50% of the patients reach adulthood with articular and/or extra articular disease activity. A careful planned transition from pediatric to adult care is necessary to reduce the loss of follow-up that is associated with stopping medications, flares, and disability due to untreated arthritis or uveitis.

Areas covered: This narrative review provides an overview of the importance of transition in JIA Articles were selected from Pubmed searches.

Expert opinion: JIA patients, family, and healthcare workers have to be trained to provide an effective transition plan, based on local and national policies. Important aspects such as expectations, maturation, disease characteristics, disease activity, adherence, disability, and psychological aspects among others have to be considered and addressed during the transition phase to improve self-esteem, self-assurance, and quality of life.

摘要

简介：幼年特发性关节炎（JIA）是儿童期最常见的风湿性炎症。随着疾病缓解药物 (DMARDs) 的早期使用和生物疾病缓解药物 (bDMARDs) 的出现，长期发病率、死亡率和生活质量有所改善。尽管治疗有所改善，但仍有约 50% 的患者在成年后出现关节和/或关节外疾病活动。有必要从儿科护理到成人护理的精心计划过渡，以减少因未治疗的关节炎或葡萄膜炎而导致的停药、发作和残疾相关的随访损失。

涵盖的领域：此叙述性评论概述了 JIA 中转换的重要性 从 Pubmed 搜索中选择的文章。

专家意见：必须对 JIA 患者、家属和医护人员进行培训，以根据地方和国家政策提供有效的过渡计划。在过渡阶段必须考虑和解决诸如期望、成熟度、疾病特征、疾病活动、依从性、残疾和心理方面等重要方面，以提高自尊、自信和生活质量。