The marine unicellular microalga Porphyridium sp. synthesizes several bioproducts consisting of sulphated polysaccharides, arachidonic acid and phycoerythrin, of which sulphated polysaccharides prominently exhibit antiviral, anticancer, anti‐inflammatory, antioxidative and immunomodulatory properties. This study aimed at appraising the feasibility of Porphyridium sp. in diets for Trachinotus ovatus. Three experimental diets were formulated to contain 0 (PS0), 10 (PS1) and 50 g/kg (PS5) Porphyridium sp. powders. After 6 weeks of feeding trials, the supplementation of Porphyridium sp. significantly boosted the growth performance and activities of digestive enzymes (pepsin and lipase). Fish fed with PS1 and PS5 diets showed greater villus length than those fed with PS0 diet. The antioxidant capacity of fish fed the diet with Porphyridium sp. powders was pronouncedly enhanced via stimulating the Nrf2‐ARE pathway and elevating antioxidant enzyme activities. Moreover, Porphyridium sp. supplementation not only promoted liver health of fish by suppressing mRNA levels of pro‐inflammatory cytokines and apoptotic genes, but significantly boosted non‐specific immunity via up‐regulating the mRNA levels of c‐type lysozyme and complement C4 and down‐regulating the mRNA levels of heat shock protein 70. These results suggest that microalga Porphyridium sp. promotes the growth performance and immune function, and thereby strengthens the health of T. ovatus.

中文翻译：

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膳食补充卟啉单胞菌后对生长性能，酶活性，免疫功能和肝脏健康的反应。在少年金po（Trachinotus ovatus）

海洋单细胞微藻卟啉单胞菌。合成了几种生物产物，其中包括硫酸化多糖，花生四烯酸和藻红蛋白，其中硫酸化多糖具有显着的抗病毒，抗癌，抗炎，抗氧化和免疫调节特性。本研究旨在评估紫菜属菌种的可行性。在卵曲霉的饮食中使用。配制了三种实验饮食，分别含有0（PS0），10（PS1）和50 g / kg（PS5）卟啉菌。粉末。经过6周的喂养试验，补充了紫菜sp。显着提高了消化酶（胃蛋白酶和脂肪酶）的生长性能和活性。饲喂PS1和PS5饲料的鱼的绒毛长度比饲喂PS0的鱼类更长。鱼用紫菜（Porphyridium sp。通过刺激Nrf2-ARE途径和提高抗氧化酶的活性，可显着增强粉末。此外，紫菜属。补充不仅通过抑制促炎性细胞因子和凋亡基因的mRNA水平来促进鱼类的肝脏健康，而且通过上调c型溶菌酶和补体C4的mRNA水平并下调mRNA的水平来显着增强非特异性免疫。热休克蛋白70的合成。这些结果表明微藻紫菜sp。促进生长性能和免疫功能，从而增强卵圆球菌的健康。