To examine the Toxocara cati larval migration in mouse fetuses through vertical transmission, 7 pregnant mice were orally inoculated with 5000 embryonated eggs at day 4 and again with the same dose at day 9 of gestation (total 10,000 eggs / mouse). Seven non-pregnant mice of the same age were also inoculated likewise. All mice were necropsied 12 days after the first inoculation with eggs. The carcass, viscera, uterus, placenta and fetuses were individually removed and digested with pepsin for larval counts. Larvae were recovered from all pregnant and non-pregnant mice. The majority of the larvae were recovered from the carcass, and some from the viscera, uterus, placenta and fetuses. There were no differences between the pregnant and non-pregnant mice for the number of larvae in the carcass, viscera and uterus. Of a total of 103 fetuses from the 7 pregnant mice, larvae were recovered from 74 fetuses (71.8 %). The mean number of larvae recovered per infected fetus was 2.6 (n = 103), and the maximum number of larvae recovered in a fetus was 9. This study showed that most mouse fetuses were infected with T. cati larvae through intrauterine transmission, although the number of larvae was low. Since no significant difference in the number of larvae recovered from the pregnant and non-pregnant mice was observed, it is suggested that pregnancy does not directly affect the vertical transmission of T. cati larvae.

检查Toxocara cati为了通过垂直传播在小鼠胎儿中的幼虫迁移，7 只怀孕小鼠在第 4 天口服接种 5000 个胚胎卵，并在妊娠第 9 天再次口服接种相同剂量（总共 10,000 个卵/小鼠）。七只同龄的非怀孕小鼠也同样接种。在第一次接种鸡蛋后 12 天对所有小鼠进行尸体剖检。尸体、内脏、子宫、胎盘和胎儿被单独取出并用胃蛋白酶消化以进行幼虫计数。从所有怀孕和未怀孕的小鼠中回收幼虫。大多数幼虫是从尸体中回收的，还有一些来自内脏、子宫、胎盘和胎儿。怀孕和未怀孕的小鼠的尸体、内脏和子宫中的幼虫数量没有差异。在来自 7 只怀孕小鼠的总共 103 个胎儿中，从 74 个胎儿 (71.8%) 中回收到幼虫。每个受感染的胎儿平均回收的幼虫数为 2.6 (n = 103)，而在一个胎儿中回收的最大幼虫数为 9。这项研究表明，大多数小鼠胎儿感染了T. cati幼虫通过宫内传播，尽管幼虫数量很少。由于观察到从怀孕和未怀孕的小鼠身上回收的幼虫数量没有显着差异，这表明怀孕不会直接影响T. cati幼虫的垂直传播。