Since 2020, the world is facing the first global pandemic of 21st century. Among all the solutions proposed to treat this new strain of coronavirus, named SARS-CoV-2, the vaccine seems a promising way but the delays are too long to be implemented quickly. In the emergency, a dual therapy has shown its effectiveness but has also provoked a set of debates around the dangerousness of a particular molecule, hydroxychloroquine. In particular, the doses to be delivered, according to the studies, were well beyond the acceptable doses to support the treatment without side effects. We propose here to use all the advantages of nanovectorization to address this question of concentration. Using quantum and classical simulations we will show in particular that drug transport on boron nitrogen oxide nanosheets increases the effectiveness of the action of these drugs. This will definitely allow to decrease the drug quantity needing to face the disease.

2020年以来，世界面临21世纪第一次全球性大流行病。在为治疗这种名为 SARS-CoV-2 的新型冠状病毒而提出的所有解决方案中，疫苗似乎是一种很有前途的方法，但延迟时间太长，无法迅速实施。在紧急情况下，双重疗法显示了其有效性，但也引发了一系列围绕特定分子羟氯喹危险性的争论。特别是，根据研究，要输送的剂量远远超出了支持治疗且没有副作用的可接受剂量。我们在这里建议利用纳米矢量化的所有优点来解决这个浓度问题。使用量子和经典模拟，我们将特别证明硼氮氧化物纳米片上的药物运输增加了这些药物作用的有效性。这肯定会减少应对疾病所需的药物数量。