Biocontrol agents and plant growth promoting microbes have emerged as promising tools for the management of plant diseases and in sustainable crop production. The present study was made to explore the potential metabolites of actinomycetes and endophytes of rice (Oryza sativa L.) and to assay the induced defence reactions in rice plants against bacterial blight (BB) of rice (Xanthomonas oryzae pv. oryzae). In-vitro studies revealed that few promising rhizospheric Streptomyces (S. fimicarius and S. laurentii) and endophytes (Pseudomonas putida and Metarhizium anisopliae) could suppress Xoo effectively in dual culture assay. P. putida + S. fimicarius + S. laurentii showed the highest (58.71%) inhibition of BB. Multiple growth promoting characteristics were assayed for these effective isolates. The effectiveness of the cell suspension (10⁷ cfu/ml) of P. putida, M. anisopliae, S. fimicarius and S. laurentii in suppressing BB of rice was tested in planta by applying as seed treatment, root treatment, soil treatment and spray application. Lowest disease incidence was observed in plants treated with the combination of P. putida + S. fimicarius + S. laurentii (10.29%) as compared to other treatments. To understand the resistance mechanisms of rice plants against Xoo, few effective secondary metabolites were assayed where the total phenol content of the treated plants showed higher concentration (2.52%). Antibiotics were recorded at a higher peak of retention time, such as pyrisulfoxin B (12.26 min), APHE 4 (13.42 min), kanamycin C (22.22 min), nitracidomycin B (15.40 min), clavulanic acid (7.89 min), neothramycin A (16.22 min), nitracidomycin A (17.78 min) and furaquinocin E (24.74 min).

生物防治剂和促进植物生长的微生物已经成为用于管理植物病害和可持续作物生产的有前途的工具。本研究是为了探索放线菌和稻（内生菌的的电位代谢物稻L.）和以测定在抗白叶枯病的水稻（BB）（稻类植物的诱导的防御反应黄单胞菌PV。米曲霉）。体外研究显示，极有希望的根际链霉菌（S. fimicarius和S. laurentii）和内生菌（Pseudomonas putida和Metrahizium anisopliae）可以抑制Xoo在双重培养分析中有效。P。恶臭 +  S。fimicarius  + 小号。laurentii对BB的抑制作用最高（58.71％）。对这些有效的分离物测定了多种促进生长的特性。P细胞悬浮液（10 ⁷  cfu / ml）的有效性。恶臭，中号。菌，小号。fimicarius和小号。在植物中测试了劳伦特抑制稻米BB的含量通过作为种子处理，根部处理，土壤处理和喷雾施用。用P组合处理的植物病害发生率最低。恶臭 +  S。fimicarius  + 小号。劳伦特（10.29％）与其他治疗相比。了解水稻对Xoo的抗性机制，几乎没有检测到有效的次生代谢产物，其中处理过的植物的总酚含量较高（2.52％）。在保留时间较高的峰上记录了抗生素，例如吡硫辛B（12.26分钟），APHE 4（13.42分钟），卡那霉素C（22.22分钟），硝酸霉素B（15.40分钟），棒酸（7.89分钟），新霉素（16.22分钟），硝酸霉素A（17.78分钟）和呋喃喹啉E（24.74分钟）。