Bacterial virulence factors play a major role in infection, which provides devastating effect on the aquaculture industry. Bacterial toxins are the major virulence factors that influence the roles of host cells and take control of living organisms’ vital processes to facilitate microbial infection. Various other bacterial virulent components such as adhesins, capsular polysaccharides, lipopolysaccharides, bacterial flagellum, pili and microbial siderophore provide a diverse effect in the microbial pathogenesis and express a variety of pathogenic molecules including aebABCEG, HutA, cpsD and pPHDD1. Bacterial protein secretion system secretes enzymes and toxins from bacterial cytoplasm to the host membrane targeting the immune cells and promoting biofilm formation. However, as they enter, the host body expresses various immune molecules that interact to utilize the pathogen recognition receptors. Toxins are powerful molecules formed by a broad range of bacterial pathogens attacking host cells and playing key roles in the dialogue between host and pathogen. They are important virulence factors that are often enough to decide the outcome of the infection. Hence, a detailed view on the virulence molecules majorly exotoxins from various bacterial pathogenic strains that are necessary to understand the pathogenesis. This review focuses on bacterial toxins and various other virulence factors, which influence the pathogenesis in fish.

中文翻译：

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养殖鱼类的致病细菌毒素和毒力影响

细菌毒力因子在感染中起主要作用，这给水产养殖业带来毁灭性影响。细菌毒素是影响宿主细胞作用并控制活生物体的关键过程以促进微生物感染的主要毒力因子。各种其他细菌有毒成分，例如粘附素，荚膜多糖，脂多糖，细菌鞭毛，菌毛和微生物铁载体，在微生物发病机理中提供多种作用，并表达多种病原性分子，包括aeb ABCEG，HutA，cps D和pPHDD1。细菌蛋白质分泌系统将细菌细胞质中的酶和毒素分泌到靶向免疫细胞并促进生物膜形成的宿主膜上。然而，当它们进入时，宿主体会表达各种免疫分子，这些分子相互作用以利用病原体识别受体。毒素是由多种细菌性病原体攻击宿主细胞并在宿主与病原体之间的对话中发挥关键作用而形成的强大分子。它们是重要的毒力因子，通常足以决定感染的结果。因此，关于毒力分子的详细视图主要是来自各种细菌致病菌株的外毒素，这对于理解发病机理是必不可少的。这篇综述着重于细菌毒素和各种其他毒力因素，这些因素会影响鱼类的发病机理。